Literature DB >> 10663023

[Post-traumatic pyoderma gangrenosum: combination therapy with intravenous immunoglobulins and systemic corticosteroids].

U S Gleichmann1, H G Otte, R Körfer, R Stadler.   

Abstract

Pyoderma gangraenosum is a rare, chronic type of skin ulceration of unknown aetiology. It occasionally appears following trauma. There are no set standards for the treatment of pyoderma gangraenosum. It is essential to consider acuteness of progression as well as underlying systemic diseases and possible drug side effects before initiating a therapy. Immunosuppressive as well as immunomodulating agents are most often used with varying degrees of success. We report a 45-year-old patient who suffered from an extensive posttraumatic pyoderma gangraenosum after cardiac bypass operation. With short-term combination therapy consisting of high dose intravenous immunoglobulins and systemic corticosteroids, the progression of the disease could be stopped within a few days.

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Year:  1999        PMID: 10663023     DOI: 10.1007/s001050051003

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  3 in total

Review 1.  Clinical uses of intravenous immunoglobulin.

Authors:  S Jolles; W A C Sewell; S A Misbah
Journal:  Clin Exp Immunol       Date:  2005-10       Impact factor: 4.330

2.  Fatal pyoderma gangrenosum with pathergy after coronary artery bypass grafting.

Authors:  Charles S Bryan
Journal:  Tex Heart Inst J       Date:  2012

3.  Pyoderma gangrenosum after cardiac surgery masquerading as a fulminant sternal wound infection.

Authors:  Kei Suzuki; Elizabeth Sieczka; Robert Tranbaugh; Darryl Hoffman
Journal:  Int J Surg Case Rep       Date:  2014-12-11
  3 in total

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