Literature DB >> 10662663

Methylation moves into medicine.

B Hendrich1.   

Abstract

Two human genetic diseases have recently been shown to be due to mutations in genes encoding proteins involved in DNA methylation. The phenotypes of these two diseases are surprisingly distinct from each other and provide insights into the functions of DNA methylation in mammals.

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Year:  2000        PMID: 10662663     DOI: 10.1016/s0960-9822(00)00286-4

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  1 in total

1.  Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylation.

Authors:  D Schübeler; M C Lorincz; D M Cimbora; A Telling; Y Q Feng; E E Bouhassira; M Groudine
Journal:  Mol Cell Biol       Date:  2000-12       Impact factor: 4.272

  1 in total

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