| Literature DB >> 10662552 |
Y Deng1, A Madan, A B Banta, C Friedman, B J Trask, L Hood, L Li.
Abstract
The genomic sequence of the human Jagged2 (JAG2) gene, which encodes a ligand for the Notch receptors, was determined. The 30-kb DNA sequence spanning the JAG2 gene contains 26 exons and a putative promoter region. Several potential binding sites for transcription factors, including NF-kappab, E47, E12, E2F, Ets-1, MyoD, and OCT-1, were found in the human JAG2 promoter region. The JAG2 gene was also mapped to the chromosomal region 14q32 using fluorescence in situ hybridization. Copyright 2000 Academic Press.Entities:
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Year: 2000 PMID: 10662552 DOI: 10.1006/geno.1999.6045
Source DB: PubMed Journal: Genomics ISSN: 0888-7543 Impact factor: 5.736