Literature DB >> 10662552

Characterization, chromosomal localization, and the complete 30-kb DNA sequence of the human Jagged2 (JAG2) gene.

Y Deng1, A Madan, A B Banta, C Friedman, B J Trask, L Hood, L Li.   

Abstract

The genomic sequence of the human Jagged2 (JAG2) gene, which encodes a ligand for the Notch receptors, was determined. The 30-kb DNA sequence spanning the JAG2 gene contains 26 exons and a putative promoter region. Several potential binding sites for transcription factors, including NF-kappab, E47, E12, E2F, Ets-1, MyoD, and OCT-1, were found in the human JAG2 promoter region. The JAG2 gene was also mapped to the chromosomal region 14q32 using fluorescence in situ hybridization. Copyright 2000 Academic Press.

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Year:  2000        PMID: 10662552     DOI: 10.1006/geno.1999.6045

Source DB:  PubMed          Journal:  Genomics        ISSN: 0888-7543            Impact factor:   5.736


  4 in total

1.  USH1A: chronicle of a slow death.

Authors:  Sylvie Gerber; Dominique Bonneau; Brigitte Gilbert; Arnold Munnich; Jean-Louis Dufier; Jean-Michel Rozet; Josseline Kaplan
Journal:  Am J Hum Genet       Date:  2006-02       Impact factor: 11.025

2.  A form of muscular dystrophy associated with pathogenic variants in JAG2.

Authors:  Sandra Coppens; Alison M Barnard; Sanna Puusepp; Sander Pajusalu; Katrin Õunap; Dorianmarie Vargas-Franco; Christine C Bruels; Sandra Donkervoort; Lynn Pais; Katherine R Chao; Julia K Goodrich; Eleina M England; Ben Weisburd; Vijay S Ganesh; Sanna Gudmundsson; Anne O'Donnell-Luria; Mait Nigul; Pilvi Ilves; Payam Mohassel; Teepu Siddique; Margherita Milone; Stefan Nicolau; Reza Maroofian; Henry Houlden; Michael G Hanna; Ros Quinlivan; Mehran Beiraghi Toosi; Ehsan Ghayoor Karimiani; Sabine Costagliola; Nicolas Deconinck; Hazim Kadhim; Erica Macke; Brendan C Lanpher; Eric W Klee; Anna Łusakowska; Anna Kostera-Pruszczyk; Andreas Hahn; Bertold Schrank; Ichizo Nishino; Masashi Ogasawara; Rasha El Sherif; Tanya Stojkovic; Isabelle Nelson; Gisèle Bonne; Enzo Cohen; Anne Boland-Augé; Jean-François Deleuze; Yao Meng; Ana Töpf; Catheline Vilain; Christina A Pacak; Marie L Rivera-Zengotita; Carsten G Bönnemann; Volker Straub; Penny A Handford; Isabelle Draper; Glenn A Walter; Peter B Kang
Journal:  Am J Hum Genet       Date:  2021-04-15       Impact factor: 11.025

3.  Analysis of Circular RNA-Related Competing Endogenous RNA Identifies the Immune-Related Risk Signature for Colorectal Cancer.

Authors:  Wei Song; Jun Ren; Chuntao Wang; Yuhang Ge; Tao Fu
Journal:  Front Genet       Date:  2020-06-03       Impact factor: 4.599

Review 4.  Notch and NF-κB: Coach and Players of Regulatory T-Cell Response in Cancer.

Authors:  Francesca Ferrandino; Paola Grazioli; Diana Bellavia; Antonio Francesco Campese; Isabella Screpanti; Maria Pia Felli
Journal:  Front Immunol       Date:  2018-10-11       Impact factor: 7.561

  4 in total

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