Literature DB >> 1066086

Multiple major cerebral artery thromboses with profound thrombocytopenia in acute leukaemia.

D G Sims, D J Scott, T C Noble.   

Abstract

A child with acute lymphoblastic leukaemia complicated by prolonged gastrointestinal and skin haemorrhages due to profound thrombocytopenia finally died of thrombotic occlusions of major cerebral arteries due to mucormycosis. Biopsy of any suspect lesion is needed urgently before prolonged therapy with amphotericin B is started. So far there have been no cures in childhood.

Entities:  

Mesh：

Year:  1976        PMID： 1066086      PMCID： PMC1545858          DOI： 10.1136/adc.51.1.74

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  7 in total

1.  Cerebral vascular disease in infancy and childhood. 1. Occlusive vascular diseases.

Authors:  B Q BANKER
Journal:  J Neuropathol Exp Neurol       Date:  1961-01       Impact factor: 3.685

2.  Phycomycetous infection (mucormycosis) in cancer patients: a complication of therapy.

Authors:  R V HUTTER
Journal:  Cancer       Date:  1959 Mar-Apr       Impact factor: 6.860

3.  Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.

Authors:  M H Tattersall; A S Spiers; J H Darrell
Journal:  Lancet       Date:  1972-01-22       Impact factor: 79.321

4.  Successfully treated rhinocerebral phycomycosis in well controlled diabetes.

Authors:  R Sandler; C B Tallman; D G Keamy; W R Irving
Journal:  N Engl J Med       Date:  1971-11-18       Impact factor: 91.245

5.  Lethal orbito-cerebral phycomycosis in otherwise healthy children.

Authors:  F C Blodi; F T Hannah; J A Wadsworth
Journal:  Am J Ophthalmol       Date:  1969-05       Impact factor: 5.258

6.  The compromised host and infection. II. Deep fungal infection.

Authors:  P D Hart; E Russell; J S Remington
Journal:  J Infect Dis       Date:  1969-08       Impact factor: 5.226

7.  Fungal infections complicating acute leukemia.

Authors:  G P Bodey
Journal:  J Chronic Dis       Date:  1966-06
  7 in total
  1 in total

1.  Role of infection in the death of children with acute lymphoblastic leukaemia.

Authors:  A W Craft; M M Reid; E Bruce; J Kernahan; P S Gardner
Journal:  Arch Dis Child       Date:  1977-10       Impact factor: 3.791
  1 in total

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