Literature DB >> 10660849

Economic impact of a rational use of antibiotics in intensive care.

P Blanc1, B E Von Elm, A Geissler, I Granier, A Boussuges, J Durand Gasselin.   

Abstract

OBJECTIVE: To evaluate the economic impact of a rational policy in antibiotic treatment.
DESIGN: Comparative study with a retrospective and a prospective part.
SETTING: An 11-bed intensive care unit (ICU) in a general hospital. PATIENTS: All patients admitted to the unit in 1994, 1995 and 1996.
INTERVENTIONS: In 1995, a program of cost control was started and a contract of agreed objectives signed with the director of the hospital. This contract included a commitment to refund the eventual savings in order to improve the quality of care. Prescribing protocols were established by consensus as guidelines for a rational policy in antibiotic therapy. MEASUREMENTS AND
RESULTS: The cost of antibiotic therapy, the patients' characteristics and the incidence of nosocomial infection were compared prior to and during the program. The expenses for antibiotic drugs decreased by 19% in 1995 and by 22% in 1996. Most of the savings were refunded to the ICU and contributed to the employment of an additional nurse and the purchase of new material. In number of patients, type of disease, mean age, Simplified Acute Physiology Score, occupancy rate, length of stay, omega score, artificial ventilation, readmission within 7 days, mortality and incidence of nosocomial infection, no significant difference was found.
CONCLUSIONS: We proved a positive economic impact of a rational policy in antibiotic therapy realized with a contract of agreed objectives. The savings made while applying our program of cost control were used to improve the quality of care.

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Year:  1999        PMID: 10660849     DOI: 10.1007/s001340051089

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN: 0342-4642            Impact factor:   17.440


  3 in total

1.  Antibiotic prescription patterns at admission into a tertiary level intensive care unit in Northern India.

Authors:  Aparna Williams; Ashu S Mathai; Atul S Phillips
Journal:  J Pharm Bioallied Sci       Date:  2011-10

2.  Drug utilization pattern in critical care unit in a tertiary care teaching hospital in India.

Authors:  Mahendra K Patel; Manish J Barvaliya; Tejas K Patel; Cb Tripathi
Journal:  Int J Crit Illn Inj Sci       Date:  2013-10

3.  Importance of nondrug costs of intravenous antibiotic therapy.

Authors:  Arthur R H van Zanten; Peter M Engelfriet; Karin van Dillen; Miriam van Veen; Mark J C Nuijten; Kees H Polderman
Journal:  Crit Care       Date:  2003-10-14       Impact factor: 9.097

  3 in total

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