OBJECTIVES: We performed single-photon emission computed tomography (SPECT) to investigate crossed cerebellocerebral diaschisis (CCCD) in patients with cerebellar stroke. MATERIAL AND METHODS: Fifteen patients with unilateral cerebellar stroke underwent SPECT of the brain with N-isopropyl-p-[123I] iodoamphetamine (123I-IMP). Regional cerebral blood flow (rCBF) was measured by the autoradiographic method. Regions of interest were defined in the cerebral cortex, striatum, thalamus and cerebellum to compare structures (contralateral to the cerebellar lesion) with counterparts ipsilateral to the stroke. RESULTS: In the frontal and parietal cortices, especially the posterior superior frontal, anterior midfrontal, precentral, postcentral, and supramarginal areas, rCBF contralateral to the lesion was significantly lower than on the side of the lesion (showing CCCD). CONCLUSION: This CCCD phenomenon is important to be aware of in clinical reading of images.
OBJECTIVES: We performed single-photon emission computed tomography (SPECT) to investigate crossed cerebellocerebral diaschisis (CCCD) in patients with cerebellar stroke. MATERIAL AND METHODS: Fifteen patients with unilateral cerebellar stroke underwent SPECT of the brain with N-isopropyl-p-[123I] iodoamphetamine (123I-IMP). Regional cerebral blood flow (rCBF) was measured by the autoradiographic method. Regions of interest were defined in the cerebral cortex, striatum, thalamus and cerebellum to compare structures (contralateral to the cerebellar lesion) with counterparts ipsilateral to the stroke. RESULTS: In the frontal and parietal cortices, especially the posterior superior frontal, anterior midfrontal, precentral, postcentral, and supramarginal areas, rCBF contralateral to the lesion was significantly lower than on the side of the lesion (showing CCCD). CONCLUSION: This CCCD phenomenon is important to be aware of in clinical reading of images.
Authors: Elisabeth Le Strange; Nadeem Saeed; Frances M Cowan; A David Edwards; Mary A Rutherford Journal: AJNR Am J Neuroradiol Date: 2004-03 Impact factor: 3.825
Authors: L Srinivasan; J Allsop; S J Counsell; J P Boardman; A D Edwards; M Rutherford Journal: AJNR Am J Neuroradiol Date: 2006-03 Impact factor: 3.825
Authors: Andreas Thieme; Markus Thürling; Julia Galuba; Roxana G Burciu; Sophia Göricke; Andreas Beck; Volker Aurich; Elke Wondzinski; Mario Siebler; Marcus Gerwig; Vlastislav Bracha; Dagmar Timmann Journal: Brain Date: 2013-05-31 Impact factor: 13.501