Literature DB >> 10660001

General linear models for multicenter clinical trials.

G Schwemer1.   

Abstract

The use of generalized linear models (GLM) in the analysis of multicenter clinical trials is commonplace. Currently, diverse opinion exists as to the proper modeling approach in this setting. This paper provides a description of the technical backdrop underlying the model selection and discusses the pros and cons of the usual parameter estimators. Arguments are given favoring a model incorporating a term for interaction effect while attenuating the effects of small centers.

Mesh:

Year:  2000        PMID: 10660001     DOI: 10.1016/s0197-2456(99)00035-5

Source DB:  PubMed          Journal:  Control Clin Trials        ISSN: 0197-2456


  4 in total

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Journal:  Hum Brain Mapp       Date:  2010-04-16       Impact factor: 5.038

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Journal:  Langenbecks Arch Surg       Date:  2012-06-24       Impact factor: 3.445

3.  Longitudinal gray matter changes in multiple sclerosis--differential scanner and overall disease-related effects.

Authors:  Kerstin Bendfeldt; Louis Hofstetter; Pascal Kuster; Stefan Traud; Nicole Mueller-Lenke; Yvonne Naegelin; Ludwig Kappos; Achim Gass; Thomas E Nichols; Frederik Barkhof; Hugo Vrenken; Stefan D Roosendaal; Jeroen J G Geurts; Ernst-Wilhelm Radue; Stefan J Borgwardt
Journal:  Hum Brain Mapp       Date:  2011-04-29       Impact factor: 5.038

4.  Do Japanese style acupuncture and moxibustion reduce symptoms of the common cold?

Authors:  Kenji Kawakita; Toshiyuki Shichidou; Etsuko Inoue; Tomoyuki Nabeta; Hiroshi Kitakoji; Shigekatsu Aizawa; Atsushi Nishida; Nobuo Yamaguchi; Norihito Takahashi; Eiji Sumiya; Kaoru Okada; Takashi Umeda; Tadashi Yano; Shouhachi Tanzawa
Journal:  Evid Based Complement Alternat Med       Date:  2007-06-11       Impact factor: 2.629

  4 in total

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