Literature DB >> 10657514

The role of galanin in feeding behavior.

J N Crawley1.   

Abstract

Galanin inhibits food consumption in satiated rats. Discovered relatively recently, galanin is a 29-amino-acid neuropeptide, not homologous with any other known peptide. Three G-protein-linked galanin receptor subtypes have been cloned. This review summarizes the mechanisms by which exogenously administered galanin may stimulate ingestion, discusses pharmacological and genetic investigations of the role of endogenous galanin on feeding and body weight, and speculates on the therapeutic potential of non-peptide galanin receptor antagonists for the treatment of appetite disorders. Copyright 1999 Harcourt Publishers Ltd.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10657514     DOI: 10.1054/npep.1999.0049

Source DB:  PubMed          Journal:  Neuropeptides        ISSN: 0143-4179            Impact factor:   3.286


  20 in total

Review 1.  Central nervous system regulation of food intake and energy expenditure: role of galanin-mediated feeding behavior.

Authors:  Peng-Hua Fang; Mei Yu; Yin-Ping Ma; Jian Li; Yu-Mei Sui; Ming-Yi Shi
Journal:  Neurosci Bull       Date:  2011-12       Impact factor: 5.203

2.  Synthesis of galmic: a nonpeptide galanin receptor agonist.

Authors:  Susana Conde Ceide; Laurent Trembleau; Gebhard Haberhauer; Laszlo Somogyi; Xiaoying Lu; Tamas Bartfai; Julius Rebek
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-19       Impact factor: 11.205

3.  Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge.

Authors:  E P Zorrilla; M Brennan; V Sabino; X Lu; T Bartfai
Journal:  Physiol Behav       Date:  2007-01-16

Review 4.  Overconsumption of dietary fat and alcohol: mechanisms involving lipids and hypothalamic peptides.

Authors:  Sarah F Leibowitz
Journal:  Physiol Behav       Date:  2007-03-30

Review 5.  Galanin: a potential role in mesolimbic dopamine-mediated instrumental behavior.

Authors:  John K Robinson; Ariel Brewer
Journal:  Neurosci Biobehav Rev       Date:  2008-06-03       Impact factor: 8.989

Review 6.  Response of substances co-expressed in hypothalamic magnocellular neurons to osmotic challenges in normal and Brattleboro rats.

Authors:  Jana Bundzikova; Zdeno Pirnik; Dora Zelena; Jens D Mikkelsen; Alexander Kiss
Journal:  Cell Mol Neurobiol       Date:  2008-09-05       Impact factor: 5.046

7.  Pharmacogenetic association of the galanin receptor (GALR1) SNP rs2717162 with smoking cessation.

Authors:  Allison B Gold; E Paul Wileyto; Adriana Lori; David Conti; Joseph F Cubells; Caryn Lerman
Journal:  Neuropsychopharmacology       Date:  2012-02-29       Impact factor: 7.853

8.  An assembly of galanin-galanin receptor signaling network.

Authors:  Lathika Gopalakrishnan; Oishi Chatterjee; Chinmayi Raj; Deepshika Pullimamidi; Jayshree Advani; Anita Mahadevan; T S Keshava Prasad
Journal:  J Cell Commun Signal       Date:  2020-11-02       Impact factor: 5.782

9.  Anticonvulsant activity of a nonpeptide galanin receptor agonist.

Authors:  Külliki Saar; Andrey M Mazarati; Riina Mahlapuu; Gerd Hallnemo; Ursel Soomets; Kalle Kilk; Sven Hellberg; Margus Pooga; Bo-Ragnar Tolf; Tiejun S Shi; Tomas Hökfelt; Claude Wasterlain; Tamas Bartfai; Ulo Langel
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-14       Impact factor: 11.205

10.  Quantitative Mass Spectrometry Reveals Food Intake-Induced Neuropeptide Level Changes in Rat Brain: Functional Assessment of Selected Neuropeptides as Feeding Regulators.

Authors:  Hui Ye; Jingxin Wang; Zichuan Tian; Fengfei Ma; James Dowell; Quentin Bremer; Gaoyuan Lu; Brian Baldo; Lingjun Li
Journal:  Mol Cell Proteomics       Date:  2017-09-01       Impact factor: 5.911

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.