| Literature DB >> 10652645 |
Abstract
In rheumatoid arthritis, synovial tissue is easily accessible for systematic analysis. Blind needle biopsy is a simple and safe procedure, but is restricted to smaller tissue samples. Arthroscopic biopsy is also safe but is more complicated as it allows access to most sites in the joint and provides adequate tissue for extensive laboratory investigations. Synovial tissue analysis has been successfully applied to studies of disease mechanisms, response to treatment and prognosis. The immuno-histological features in synovial tissue have consistently reflected disease status. Synovial tissue analysis has been particularly informative in the study of novel therapeutic agents.Entities:
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Year: 1999 PMID: 10652645 DOI: 10.1053/berh.1999.0051
Source DB: PubMed Journal: Baillieres Best Pract Res Clin Rheumatol ISSN: 1521-6942 Impact factor: 4.098