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Literature DB >> 10652498

Signal transduction from the angiotensin II AT2 receptor.

Abstract

Recent studies of genetically engineered animals have established a role for the angiotensin II (AT2) receptor in cardiovascular, renal and central functions, as well as in developmental processes. This review summarizes new insights into major AT2 signaling pathways--activation of protein phosphatases, the nitric oxide-cGMP system and phospholipase A2--which have been related to specific cellular responses or functions of this receptor.

Entities: Chemical Gene

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Year: 2000 PMID： 10652498 DOI： 10.1016/s1043-2760(99)00205-2

Source DB: PubMed Journal: Trends Endocrinol Metab ISSN： 1043-2760 Impact factor: 12.015

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Cited

29 in total

Review 1. Angiotensin and calcium signaling in the pituitary and hypothalamus.

Authors: Cecilia Suárez; Isabel García Tornadú; Carolina Cristina; Jorge Vela; Arturo González Iglesias; Carlos Libertun; Graciela Díaz-Torga; Damasia Becu-Villalobos
Journal: Cell Mol Neurobiol Date: 2002-06 Impact factor: 5.046

Review 2. Local renin-angiotensin systems in the genitourinary tract.

Authors: Craig Comiter
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2011-11-13 Impact factor: 3.000

3. Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells.

Authors: Young H Lee; Ognoon Mungunsukh; Rebecca L Tutino; Ana P Marquez; Regina M Day
Journal: J Cell Sci Date: 2010-04-20 Impact factor: 5.285

Review 4. Novel therapeutic targets for hypertension.

Authors: Ludovit Paulis; Thomas Unger
Journal: Nat Rev Cardiol Date: 2010-06-22 Impact factor: 32.419

Review 5. International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].

Authors: Sadashiva S Karnik; Hamiyet Unal; Jacqueline R Kemp; Kalyan C Tirupula; Satoru Eguchi; Patrick M L Vanderheyden; Walter G Thomas
Journal: Pharmacol Rev Date: 2015-10 Impact factor: 25.468

Review 6. The role of the cell-matrix interface in aging and its interaction with the renin-angiotensin system in the aged vasculature.

Authors: Maria De Luca
Journal: Mech Ageing Dev Date: 2018-04-04 Impact factor: 5.432

Signal transduction from the angiotensin II AT2 receptor.

Review 1. Angiotensin and calcium signaling in the pituitary and hypothalamus.

Review 2. Local renin-angiotensin systems in the genitourinary tract.

3. Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells.

Review 4. Novel therapeutic targets for hypertension.

Review 5. International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].

Review 6. The role of the cell-matrix interface in aging and its interaction with the renin-angiotensin system in the aged vasculature.

7. Age-dependent differential crosstalk between alpha(1)-adrenergic and angiotensin receptors.

8. Identification of a Primary Renal AT₂ Receptor Defect in Spontaneously Hypertensive Rats.

Review 9. Angiotensin II and nitric oxide interaction.

Review 10. Impact of the AT(2) receptor agonist C21 on blood pressure and beyond.

Signal transduction from the angiotensin II AT2 receptor.

Review 1. Angiotensin and calcium signaling in the pituitary and hypothalamus.

Review 2. Local renin-angiotensin systems in the genitourinary tract.

3. Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells.

Review 4. Novel therapeutic targets for hypertension.

Review 5. International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].

Review 6. The role of the cell-matrix interface in aging and its interaction with the renin-angiotensin system in the aged vasculature.

7. Age-dependent differential crosstalk between alpha(1)-adrenergic and angiotensin receptors.

8. Identification of a Primary Renal AT2 Receptor Defect in Spontaneously Hypertensive Rats.

Review 9. Angiotensin II and nitric oxide interaction.

Review 10. Impact of the AT(2) receptor agonist C21 on blood pressure and beyond.

8. Identification of a Primary Renal AT₂ Receptor Defect in Spontaneously Hypertensive Rats.