Literature DB >> 10651322

Compensatory restorative processes and operant reflexes in rats after neurotoxin lesioning of the inferior olive.

V V Fanardzhyan1, E A Oganesyan, A B Melik-Musyan, E V Papoyan, O V Govorkyan.   

Abstract

Studies on rats showed that complete neurotoxin lesioning of the inferior olive obviated the possibility of developing and restoring previously learned operant balance reflexes. Motor deficit and compensatory-restorative processes in rats treated with 3-acetylpyridine and high section of the dorsolateral funiculus of the spinal cord depended directly on the level of disruption of the inferior olive. Prolonged observation of rats with incomplete lesions to the inferior olive revealed improvements in the compensation of motor lesions and stabilization of operant reflexes.

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Year:  1999        PMID: 10651322     DOI: 10.1007/bf02462480

Source DB:  PubMed          Journal:  Neurosci Behav Physiol        ISSN: 0097-0549


  14 in total

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Authors:  R Llinás; K Walton; D E Hillman; C Sotelo
Journal:  Science       Date:  1975-12-19       Impact factor: 47.728

2.  Role of the inferior olivary complex in motor skills and motor learning in the adult rat.

Authors:  L Rondi-Reig; N Delhaye-Bouchaud; J Mariani; J Caston
Journal:  Neuroscience       Date:  1997-04       Impact factor: 3.590

Review 3.  Corticospinal, rubrospinal and rubro-olivary projections: a unifying hypothesis.

Authors:  P R Kennedy
Journal:  Trends Neurosci       Date:  1990-12       Impact factor: 13.837

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Authors:  P F Gilbert; W T Thach
Journal:  Brain Res       Date:  1977-06-10       Impact factor: 3.252

Review 5.  Reciprocal trophic interactions in the adult climbing fibre-Purkinje cell system.

Authors:  F Rossi; P Strata
Journal:  Prog Neurobiol       Date:  1995 Nov-Dec       Impact factor: 11.685

6.  The compensatory role of the parvocellular division of the red nucleus in operantly conditioned rats.

Authors:  P R Kennedy; D R Humphrey
Journal:  Neurosci Res       Date:  1987-10       Impact factor: 3.304

7.  On the inferior olive of the albino rat.

Authors:  R F Schild
Journal:  J Comp Neurol       Date:  1970-11       Impact factor: 3.215

8.  A theory of cerebellar cortex.

Authors:  D Marr
Journal:  J Physiol       Date:  1969-06       Impact factor: 5.182

9.  Reinnervation of cerebellar Purkinje cells by climbing fibres surviving a subtotal lesion of the inferior olive in the adult rat. I. Development of new collateral branches and terminal plexuses.

Authors:  F Rossi; L Wiklund; J J van der Want; P Strata
Journal:  J Comp Neurol       Date:  1991-06-22       Impact factor: 3.215

10.  Effects of lesion of the inferior olivary complex in learning of the equilibrium behavior in the young rat during ontogenesis. I. Total lesion of the inferior olive by 3-acetylpyridine.

Authors:  N Jones; T Stelz; C Batini; J Caston
Journal:  Brain Res       Date:  1995-10-30       Impact factor: 3.252

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