Literature DB >> 10650251

How gastroenterologists screen for colonic cancer in ulcerative colitis: an analysis of performance.

J A Eaden1, B A Ward, J F Mayberry.   

Abstract

BACKGROUND: The aim of this study was to assess the colorectal cancer surveillance practices of British gastroenterologists for patients with ulcerative colitis.
METHODS: A questionnaire that investigated aspects of surveillance in patients with ulcerative colitis was mailed to all consultant gastroenterologists in the U.K. (n = 413).
RESULTS: Three hundred forty-one questionnaires were returned (response rate 83%). Ninety-four percent of consultants practice cancer surveillance in ulcerative colitis, with 35% maintaining a registry of patients in surveillance programs. All gastroenterologists perform surveillance in patients with pancolitis, 24% in those with left-sided colitis and 2% in patients with proctitis. The mean duration of disease before surveillance is commenced is 9.2 years for pancolitis and 12.4 years for left-sided colitis (p < 0.0001). Only 4% of gastroenterologists routinely offer patients with disease of more than 10 years' duration a prophylactic colectomy. Colonoscopies are conducted by an accredited gastroenterologist in 65% of cases and biopsies are reviewed by specialists in gastrointestinal pathology in 45%. When histology reveals low-grade dysplasia only 4% advise colectomy and when high-grade dysplasia is found 53% recommend colectomy. Sixteen percent of gastroenterologists were unaware of the significance of a dysplasia associated lesion or mass.
CONCLUSION: The majority of gastroenterologists practice surveillance on a disorganized basis. There is inconsistency in the management of patients with dysplasia and education of gastroenterologists is needed.

Entities:  

Mesh:

Year:  2000        PMID: 10650251     DOI: 10.1016/s0016-5107(00)70405-6

Source DB:  PubMed          Journal:  Gastrointest Endosc        ISSN: 0016-5107            Impact factor:   9.427


  54 in total

Review 1.  Diagnostic methodologies: serology, endoscopy, and radiology.

Authors:  T Dassopoulos
Journal:  Curr Gastroenterol Rep       Date:  2001-12

2.  Surveillance colonoscopy in patients with inflammatory bowel disease: comparison of random biopsy vs. targeted biopsy protocols.

Authors:  Ute Günther; Dajana Kusch; Frank Heller; Nataly Bürgel; Silke Leonhardt; Severin Daum; Britta Siegmund; Christoph Loddenkemper; Maria Grünbaum; Heinz-Johannes Buhr; Jörg-Dieter Schulzke; Martin Zeitz; Christian Bojarski
Journal:  Int J Colorectal Dis       Date:  2011-01-29       Impact factor: 2.571

3.  Protagonist: Early surgical intervention in ulcerative colitis.

Authors:  R R Cima; J H Pemberton
Journal:  Gut       Date:  2004-02       Impact factor: 23.059

4.  Screening and surveillance for asymptomatic colorectal cancer in IBD.

Authors:  A Forbes; S Gabe; J E Lennard-Jones; K Wilkinson
Journal:  Gut       Date:  2003-05       Impact factor: 23.059

Review 5.  The management of dysplasia associated with ulcerative colitis: colectomy versus continued surveillance.

Authors:  Martin S Friedlich; Maha Guindi; Hartley S Stern
Journal:  Can J Surg       Date:  2004-06       Impact factor: 2.089

6.  Random versus targeted biopsies for colorectal cancer surveillance in inflammatory bowel disease.

Authors:  Tasneem Ahmed; Jennifer Monti; Bret Lashner
Journal:  Gastroenterol Hepatol (N Y)       Date:  2010-07

Review 7.  Quality of care in inflammatory bowel disease.

Authors:  Brijen Shah; Andrew Tinsley; Thomas Ullman
Journal:  Curr Gastroenterol Rep       Date:  2011-02

8.  Simultaneous detection of synchronous colonic and biliary carcinoma by abdominal ultrasonography in two patients with ulcerative colitis.

Authors:  R D Klingenberg-Noftz; N Homann; I Bos; H P Bruch; D Ludwig
Journal:  Dig Dis Sci       Date:  2004 Nov-Dec       Impact factor: 3.199

9.  British Society of Gastroenterology guidelines for ulcerative colitis surveillance: creating consensus or confusion?

Authors:  B Hudson; J Green
Journal:  Gut       Date:  2006-07       Impact factor: 23.059

10.  Colorectal neoplasia in IBD--a single-center analysis of patients undergoing proctocolectomy.

Authors:  Rüdiger Meyer; Tilman Laubert; Martin Sommer; Claudia Benecke; Hendrik Lehnert; Klaus Fellermann; Hans-Peter Bruch; Tobias Keck; Christoph Thorns; Jens K Habermann; Jürgen Büning
Journal:  Int J Colorectal Dis       Date:  2015-04-26       Impact factor: 2.571

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.