Literature DB >> 10650166

Neuropeptide-Y exerts antidepressant-like effects in the forced swim test in rats.

K A Stogner1, P V Holmes.   

Abstract

The effects of neuropeptide-Y were examined in the forced swim model of depression in rats. Following a 15-min preswim, four groups of rats were given three intracerebroventricular (i.c.v.) injections of neuropeptide-Y (0.5, 5, or 10 microg) or saline over a 24-h period. Several behaviors were subsequently measured during a 5-min forced swim. Neuropeptide-Y treatment dose dependently increased swimming and decreased immobility. The pattern of results is consistent with that produced by serotonergic antidepressant drugs in this model.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10650166     DOI： 10.1016/s0014-2999(99)00800-6

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  34 in total

Review 1.  Tobacco addiction and the dysregulation of brain stress systems.

Authors:  Adrie W Bruijnzeel
Journal:  Neurosci Biobehav Rev       Date:  2012-03-03       Impact factor: 8.989

2.  Effects of prolonged ethanol vapor exposure on forced swim behavior, and neuropeptide Y and corticotropin-releasing factor levels in rat brains.

Authors:  Brendan M Walker; David A Drimmer; Jennifer L Walker; Tianmin Liu; Aleksander A Mathé; Cindy L Ehlers
Journal:  Alcohol       Date:  2010-08-12       Impact factor: 2.405

3.  Effects of NPY and the specific Y1 receptor agonist [D-His(26)]-NPY on the deficit in brain reward function and somatic signs associated with nicotine withdrawal in rats.

Authors:  Daria Rylkova; Jeffrey Boissoneault; Shani Isaac; Melissa Prado; Hina P Shah; Adrie W Bruijnzeel
Journal:  Neuropeptides       Date:  2008-05-12       Impact factor: 3.286

4.  Sexual deprivation increases ethanol intake in Drosophila.

Authors:  G Shohat-Ophir; K R Kaun; R Azanchi; H Mohammed; U Heberlein
Journal:  Science       Date:  2012-03-16       Impact factor: 47.728

Review 5.  Neuropeptide Y and posttraumatic stress disorder.

Authors:  R Sah; T D Geracioti
Journal:  Mol Psychiatry       Date:  2012-07-17       Impact factor: 15.992

6.  Repeated gastric distension alters food intake and neuroendocrine profiles in rats.

Authors:  Sara L Hargrave; Kimberly P Kinzig
Journal:  Physiol Behav       Date:  2011-11-15

7.  Emotional behavior in aged neuropeptide Y (NPY) Y2 knockout mice.

Authors:  Cristina Carvajal; Yvan Dumont; Herbert Herzog; Rémi Quirion
Journal:  J Mol Neurosci       Date:  2006       Impact factor: 3.444

8.  The neuropeptide VGF produces antidepressant-like behavioral effects and enhances proliferation in the hippocampus.

Authors:  Smita Thakker-Varia; Jennifer Jernstedt Krol; Jacob Nettleton; Parizad M Bilimoria; Debra A Bangasser; Tracey J Shors; Ira B Black; Janet Alder
Journal:  J Neurosci       Date:  2007-11-07       Impact factor: 6.167

Review 9.  Trends in the development of new antidepressants. Is there a light at the end of the tunnel?

Authors:  Pal Pacher; Valeria Kecskemeti
Journal:  Curr Med Chem       Date:  2004-04       Impact factor: 4.530

Review 10.  Neuropeptides in depression: role of VGF.

Authors:  Smita Thakker-Varia; Janet Alder
Journal:  Behav Brain Res       Date:  2008-10-15       Impact factor: 3.332
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.