Literature DB >> 10650100

A cytotoxic 5alpha,8alpha-epidioxysterol from a soft coral Sinularia species.

J H Sheu1, K C Chang, C Y Duh.   

Abstract

A new sterol, (22R,23R,24R)-5alpha,8alpha-epidioxy-22, 23-methylene-24-methylcholest-6-en-3beta-ol (1), as well as two known sterols, numersterol A (2) and pregnenolone (3), have been isolated from a soft coral Sinularia sp. The structure of metabolite 1 was determined by spectral analysis. Cytotoxicity of sterols 1-3 toward various cancer cell lines is also reported.

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Year:  2000        PMID： 10650100     DOI： 10.1021/np9903954

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction.

Authors:  Sujatha Ramasamy; Norhanom Abdul Wahab; Nurhayati Zainal Abidin; Sugumaran Manickam; Zubaidah Zakaria
Journal:  PLoS One       Date:  2012-04-20       Impact factor: 3.240

2.  New sinularianin sesquiterpenes from soft coral Sinularia sp.

Authors:  Bin Yang; Shengrong Liao; Xiuping Lin; Junfeng Wang; Juan Liu; Xuefeng Zhou; Xianwen Yang; Yonghong Liu
Journal:  Mar Drugs       Date:  2013-12-02       Impact factor: 5.118

Review 3.  Cytotoxic Compounds from Alcyoniidae: An Overview of the Last 30 Years.

Authors:  Federico Cerri; Francesco Saliu; Davide Maggioni; Simone Montano; Davide Seveso; Silvia Lavorano; Luca Zoia; Fabio Gosetti; Marina Lasagni; Marco Orlandi; Orazio Taglialatela-Scafati; Paolo Galli
Journal:  Mar Drugs       Date:  2022-02-11       Impact factor: 5.118

4.  Polyoxygenated sterols from the South China Sea soft coral Sinularia sp.

Authors:  Rui Li; Chang-Lun Shao; Xin Qi; Xiu-Bao Li; Jing Li; Ling-Ling Sun; Chang-Yun Wang
Journal:  Mar Drugs       Date:  2012-06-26       Impact factor: 6.085

Review 5.  Cytotoxic and cytolytic cnidarian venoms. A review on health implications and possible therapeutic applications.

Authors:  Gian Luigi Mariottini; Luigi Pane
Journal:  Toxins (Basel)       Date:  2013-12-27       Impact factor: 4.546

6.  Microalgal Microscale Model for Microalgal Growth Inhibition Evaluation of Marine Natural Products.

Authors:  Qing Zhao; An-Na Chen; Shun-Xin Hu; Qian Liu; Min Chen; Lu Liu; Chang-Lun Shao; Xue-Xi Tang; Chang-Yun Wang
Journal:  Sci Rep       Date:  2018-07-12       Impact factor: 4.379
  6 in total

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