Literature DB >> 10649537

Memory and learning are not impaired in presymptomatic individuals with an increased risk of Huntington's disease.

G M de Boo1, A A Tibben, J A Hermans, A Jennekens-Schinkel, A Maat-Kievit, R A Roos.   

Abstract

Retrieval from long-term memory in patients with brain injuries was investigated with a memory scanning paradigm (Conway & Engle, 1994), that allows dissociation of scanning processes within short-term memory and memory retrieval processes from long-term memory. The study focused on the influence of brain injury on memory retrieval processes that are assumed to be automatic. Thirteen patients with memory impairment and 13 healthy matched control subjects were tested. In general, patients showed increased reaction times, but they showed set size independent retrieval from long-term memory indicating preserved automatic retrieval processes. In a subgroup of patients with more severe memory deficits, however, automatic retrieval processes appeared not to be intact. Learning profiles of the patients were characterized by smaller item chunks, indicating differences in the process of information acquisition.

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Year:  1999        PMID: 10649537     DOI: 10.1076/jcen.21.6.831.854

Source DB:  PubMed          Journal:  J Clin Exp Neuropsychol        ISSN: 1380-3395            Impact factor:   2.475


  7 in total

1.  Verbal episodic memory declines prior to diagnosis in Huntington's disease.

Authors:  Andrea C Solomon; Julie C Stout; Shannon A Johnson; Douglas R Langbehn; Elizabeth H Aylward; Jason Brandt; Christopher A Ross; Leigh Beglinger; Michael R Hayden; Karl Kieburtz; Elise Kayson; Elaine Julian-Baros; Kevin Duff; Mark Guttman; Martha Nance; David Oakes; Ira Shoulson; Elizabeth Penziner; Jane S Paulsen
Journal:  Neuropsychologia       Date:  2007-01-09       Impact factor: 3.139

2.  Subtle changes among presymptomatic carriers of the Huntington's disease gene.

Authors:  S C Kirkwood; E Siemers; M E Hodes; P M Conneally; J C Christian; T Foroud
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-12       Impact factor: 10.154

3.  Parallel explicit and implicit control of reaching.

Authors:  Pietro Mazzoni; Nancy S Wexler
Journal:  PLoS One       Date:  2009-10-22       Impact factor: 3.240

4.  Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation--a longitudinal follow-up study.

Authors:  Jurgen Lemiere; Marleen Decruyenaere; Gery Evers-Kiebooms; Erik Vandenbussche; Rene Dom
Journal:  J Neurol       Date:  2004-08       Impact factor: 4.849

5.  Progression in prediagnostic Huntington disease.

Authors:  Jason Rupp; Tanya Blekher; Jacqueline Jackson; Xabier Beristain; Jeanine Marshall; Siu Hui; Joanne Wojcieszek; Tatiana Foroud
Journal:  J Neurol Neurosurg Psychiatry       Date:  2009-09-01       Impact factor: 10.154

6.  Neuropsychological deficits in Huntington's disease gene carriers and correlates of early "conversion".

Authors:  Jason Brandt; Anjeli B Inscore; Julianna Ward; Barnett Shpritz; Adam Rosenblatt; Russell L Margolis; Christopher A Ross
Journal:  J Neuropsychiatry Clin Neurosci       Date:  2008       Impact factor: 2.198

7.  Motor-Language Coupling in Huntington's Disease Families.

Authors:  Lucila Kargieman; Eduar Herrera; Sandra Baez; Adolfo M García; Martin Dottori; Carlos Gelormini; Facundo Manes; Oscar Gershanik; Agustín Ibáñez
Journal:  Front Aging Neurosci       Date:  2014-06-12       Impact factor: 5.750

  7 in total

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