Literature DB >> 10648

Correlation of graft-versus-host mortality and positive CML assay in the mouse.

W L Elkins.   

Abstract

GVH mortality was encountered in each of six parental-F1 hybrid combinations with antigenic disparity sufficient to cause strong positive CML. Mortality was encountered in only one of nine combinations in which CML is negative (or weak). The CML assay may thus be useful, but is not perfect, in prediction of GVH mortality. Of the eight CML-negative, GVH nonlethal combinations, three were MLC positive and also activated donor T-cell proliferation in vivo.

Entities:  

Mesh：

Year:  1976        PMID： 10648

Source DB:  PubMed          Journal:  Transplant Proc        ISSN： 0041-1345            Impact factor:   1.066


  5 in total

1.  Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences.

Authors:  J Sprent; M Schaefer; D Lo; R Korngold
Journal:  J Exp Med       Date:  1986-04-01       Impact factor: 14.307

2.  Capacity of genetically different T lymphocytes to induce lethal graft-versus-host disease correlates with their capacity to generate suppression but not with their capacity to generate anti-F1 killer cells. A non-H-2 locus determines the inability to induce lethal graft-versus-host disease.

Authors:  E H Van Elven; A G Rolink; F V Veen; E Gleichmann
Journal:  J Exp Med       Date:  1981-06-01       Impact factor: 14.307

3.  The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice.

Authors:  M B Baker; N H Altman; E R Podack; R B Levy
Journal:  J Exp Med       Date:  1996-06-01       Impact factor: 14.307

4.  Allosuppressor and allohelper T cells in acute and chronic graft-vs-host disease. I. Alloreactive suppressor cells rather than killer T cells appear to be the decisive effector cells in lethal graft-vs.-host disease.

Authors:  A G Rolink; T Radaszkiewicz; S T Pals; W G van der Meer; E Gleichmann
Journal:  J Exp Med       Date:  1982-05-01       Impact factor: 14.307

5.  Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow.

Authors:  R Korngold; J Sprent
Journal:  J Exp Med       Date:  1978-12-01       Impact factor: 14.307
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.