Literature DB >> 10647039

Prevention of vertical transfer of Neospora caninum in BALB/c mice by vaccination.

S Liddell1, M C Jenkins, C M Collica, J P Dubey.   

Abstract

Neosporosis is an important cause of abortion and neonatal morbidity in dairy cattle. The disease is caused by Neospora caninum, an intracellular protozoan parasite. In this report, we describe the use of a mouse model in the preliminary evaluation of vaccination as a means to prevent vertical transfer of N. caninum. Parasites present in the tissues of the offspring were detected using an N. caninum-specific polymerase chain reaction assay. Immunization of dams with a single inoculation of a crude lysate of N. caninum tachyzoites appeared to induce complete protection against infection of the offspring.

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Year:  1999        PMID： 10647039

Source DB:  PubMed          Journal:  J Parasitol        ISSN： 0022-3395            Impact factor:   1.276


  10 in total

1.  Inclusion of CpG adjuvant with plasmid DNA coding for NcGRA7 improves protection against congenital neosporosis.

Authors:  Mark Jenkins; Carolyn Parker; Wenbin Tuo; Bryan Vinyard; J P Dubey
Journal:  Infect Immun       Date:  2004-03       Impact factor: 3.441

2.  Protective effect of intranasal immunization with Neospora caninum membrane antigens against murine neosporosis established through the gastrointestinal tract.

Authors:  Pedro Ferreirinha; Joana Dias; Alexandra Correia; Begoña Pérez-Cabezas; Carlos Santos; Luzia Teixeira; Adília Ribeiro; António Rocha; Manuel Vilanova
Journal:  Immunology       Date:  2014-02       Impact factor: 7.397

3.  Protective efficacy of vaccination with Neospora caninum multiple recombinant antigens against experimental Neospora caninum infection.

Authors:  Jung-Hwa Cho; Woo-Suk Chung; Kyoung-Ju Song; Byoung-Kuk Na; Seung-Won Kang; Chul-Yong Song; Tong-Soo Kim
Journal:  Korean J Parasitol       Date:  2005-03       Impact factor: 1.341

4.  Immunization of cattle with live tachyzoites of Neospora caninum confers protection against fetal death.

Authors:  D J L Williams; C S Guy; R F Smith; J Ellis; C Björkman; M P Reichel; A J Trees
Journal:  Infect Immun       Date:  2006-12-04       Impact factor: 3.441

5.  The role of B- and T-cell immunity in toltrazuril-treated C57BL/6 WT, microMT and nude mice experimentally infected with Neospora caninum.

Authors:  Petra Ammann; Andreas Waldvogel; Isabel Breyer; Marco Esposito; Norbert Müller; Bruno Gottstein
Journal:  Parasitol Res       Date:  2004-06       Impact factor: 2.289

6.  Immunization with oligomannose-coated liposome-entrapped dense granule protein 7 protects dams and offspring from Neospora caninum infection in mice.

Authors:  Yoshifumi Nishikawa; Houshuang Zhang; Yuzuru Ikehara; Naoya Kojima; Xuenan Xuan; Naoaki Yokoyama
Journal:  Clin Vaccine Immunol       Date:  2009-04-08

7.  Toltrazuril treatment of congenitally acquired Neospora caninum infection in newborn mice.

Authors:  M Strohbusch; N Müller; A Hemphill; R Krebber; G Greif; B Gottstein
Journal:  Parasitol Res       Date:  2009-02-10       Impact factor: 2.289

Review 8.  Epidemiology and control of neosporosis and Neospora caninum.

Authors:  J P Dubey; G Schares; L M Ortega-Mora
Journal:  Clin Microbiol Rev       Date:  2007-04       Impact factor: 26.132

Review 9.  Vaccines against a Major Cause of Abortion in Cattle, Neospora caninum Infection.

Authors:  Thierry Monney; Karim Debache; Andrew Hemphill
Journal:  Animals (Basel)       Date:  2011-09-08       Impact factor: 2.752

10.  Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model.

Authors:  Thierry Monney; Denis Grandgirard; Stephen L Leib; Andrew Hemphill
Journal:  Pathogens       Date:  2013-03-27
  10 in total

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