| Literature DB >> 10646941 |
A J Salinas1, J Román, M Vallet-Regí, J M Oliveira, R N Correia, M H Fernandes.
Abstract
A glass of nominal composition (wt%) 40.0 CaO-34.5 SiO2-16.5 P2O5-8.5 MgO-0.5 CaF2 has been obtained (G13). The glass showed in vitro bioactivity evidenced by the formation on its surface of a calcium phosphate-rich layer when soaked in a solution with ionic composition analogous to human plasma. By thermal treatments of G13, a glass-ceramic (GC13) containing apatite, diopside, althausite and akermanite as crystalline phases was developed. GC13 as-made did not show in vitro bioactivity. However, after chemical treatment of GC13 with 1 M HCl (GC13-HCl), the in vitro studies showed the formation of an apatite-like layer covering certain areas of the material surface. The influence of both chemical and morphological factors on the in vitro bioactivity has been studied.Entities:
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Year: 2000 PMID： 10646941 DOI： 10.1016/s0142-9612(99)00150-7
Source DB: PubMed Journal: Biomaterials ISSN： 0142-9612 Impact factor: 12.479