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Literature DB >> 10645172

Angiogenesis in cancer: the role of endothelin-1.

K Dawas¹, M Loizidou, A Shankar, H Ali, I Taylor.

Abstract

This review summarises the process of angiogenesis, its role in tumourigenesis and suggests a mechanism by which endothelin-1 may influence these processes.

Entities: Disease Gene

Mesh：

Substances：
Endothelin-1

Year: 1999 PMID： 10645172 PMCID： PMC2503288

Source DB: PubMed Journal: Ann R Coll Surg Engl ISSN： 0035-8843 Impact factor: 1.891

44 in total

1. Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from tumor cells and blockage by PPS of tumor growth in animals.

Authors: G Zugmaier; M E Lippman; A Wellstein
Journal: J Natl Cancer Inst Date: 1992-11-18 Impact factor: 13.506

2. Production of endothelin in human cancer cell lines.

Authors: M Kusuhara; K Yamaguchi; K Nagasaki; C Hayashi; A Suzaki; S Hori; S Handa; Y Nakamura; K Abe
Journal: Cancer Res Date: 1990-06-01 Impact factor: 12.701

3. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium.

Authors: G H Fong; J Rossant; M Gertsenstein; M L Breitman
Journal: Nature Date: 1995-07-06 Impact factor: 49.962

4. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice.

Authors: F Shalaby; J Rossant; T P Yamaguchi; M Gertsenstein; X F Wu; M L Breitman; A C Schuh
Journal: Nature Date: 1995-07-06 Impact factor: 49.962

Review 5. Endothelin: potential role in hypertension and vascular hypertrophy.

Authors: E L Schiffrin
Journal: Hypertension Date: 1995-06 Impact factor: 10.190

6. High plasma concentrations of endothelin-like immunoreactivities in patients with hepatocellular carcinoma.

Authors: M Nakamuta; M Ohashi; S Tabata; Y Tanabe; K Goto; M Naruse; K Naruse; K Hiroshige; H Nawata
Journal: Am J Gastroenterol Date: 1993-02 Impact factor: 10.864

7. Endothelin antagonists improve renal function in spontaneously hypertensive rats.

Authors: T Kato; S Kassab; F C Wilkins; K A Kirchner; J Keiser; J P Granger
Journal: Hypertension Date: 1995-04 Impact factor: 10.190

8. A selective endothelin ETA antagonist, BQ-123, inhibits 125I-endothelin-1 (125I-ET-1) binding to human meningiomas and antagonizes ET-1-induced proliferation of meningioma cells.

Authors: N Kitagawa; K Tsutsumi; M Niwa; S Yamaga; T Anda; H Khalid; A Himeno; K Taniyama; S Shibata
Journal: Cell Mol Neurobiol Date: 1994-04 Impact factor: 5.046

Angiogenesis in cancer: the role of endothelin-1.

1. Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from tumor cells and blockage by PPS of tumor growth in animals.

2. Production of endothelin in human cancer cell lines.

3. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium.

4. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice.

Review 5. Endothelin: potential role in hypertension and vascular hypertrophy.

6. High plasma concentrations of endothelin-like immunoreactivities in patients with hepatocellular carcinoma.

7. Endothelin antagonists improve renal function in spontaneously hypertensive rats.

8. A selective endothelin ETA antagonist, BQ-123, inhibits 125I-endothelin-1 (125I-ET-1) binding to human meningiomas and antagonizes ET-1-induced proliferation of meningioma cells.

9. The role of vascular endothelial growth factor in blood vessel formation.

10. Relationship between vasculogenesis, angiogenesis and haemopoiesis during avian ontogeny.

1. Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo.

2. Role of endothelin-1 in neovascularization of ovarian carcinoma.

Review 3. Role of endothelin-1 in lung disease.

Review 4. Treatment of Cancer Pain by Targeting Cytokines.