Literature DB >> 10642859

Saffron extract prevents acetaldehyde-induced inhibition of long-term potentiation in the rat dentate gyrus in vivo.

K Abe1, M Sugiura, S Yamaguchi, Y Shoyama, H Saito.   

Abstract

We have previously found that alcohol extract of Crocus sativus L. (CSE), commonly known as saffron, prevents ethanol-induced inhibition of hippocampal long-term potentiation (LTP). In the present study, CSE (250 mg/kg, p.o.) was also effective in preventing acetaldehyde-induced inhibition of LTP in the dentate gyrus of anesthetized rats. These results suggest that CSE can prevent aversive effects induced by ethanol and its metabolite acetaldehyde.

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Year:  1999        PMID： 10642859     DOI： 10.1016/s0006-8993(99)02174-5

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  11 in total

1.  Crocus sativus Extract Tightens the Blood-Brain Barrier, Reduces Amyloid β Load and Related Toxicity in 5XFAD Mice.

Authors:  Yazan S Batarseh; Sonali S Bharate; Vikas Kumar; Ajay Kumar; Ram A Vishwakarma; Sandip B Bharate; Amal Kaddoumi
Journal:  ACS Chem Neurosci       Date:  2017-05-15       Impact factor: 4.418

Review 2.  Crocetin: an agent derived from saffron for prevention and therapy for cancer.

Authors:  William G Gutheil; Gregory Reed; Amitabha Ray; Shrikant Anant; Animesh Dhar
Journal:  Curr Pharm Biotechnol       Date:  2012-01       Impact factor: 2.837

3.  Crocus sativus L.: A comprehensive review.

Authors:  R Srivastava; H Ahmed; R K Dixit; S A Saraf
Journal:  Pharmacogn Rev       Date:  2010-07

4.  Neuroprotective efficacy of Nardostachys jatamansi and crocetin in conjunction with selenium in cognitive impairment.

Authors:  M Badruzzaman Khan; Md Nasrul Hoda; Tauheed Ishrat; Saif Ahmad; Mohd Moshahid Khan; Ajmal Ahmad; Seema Yusuf; Fakhrul Islam
Journal:  Neurol Sci       Date:  2011-12-15       Impact factor: 3.307

Review 5.  Crocus Sativus L. (Saffron) in Alzheimer's Disease Treatment: Bioactive Effects on Cognitive Impairment.

Authors:  Grazia D'Onofrio; Seyed Mohammad Nabavi; Daniele Sancarlo; Antonio Greco; Stefano Pieretti
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.363

6.  Saffron supplements modulate serum pro-oxidant-antioxidant balance in patients with metabolic syndrome: A randomized, placebo-controlled clinical trial.

Authors:  Tayyebeh Kermani; Seyyed Hadi Mousavi; Maryam Shemshian; Abdolreza Norouzy; Mohsen Mazidi; Atefeh Moezzi; Toktam Moghiman; Majid Ghayour-Mobarhan; Gordon A Ferns
Journal:  Avicenna J Phytomed       Date:  2015 Sep-Oct

Review 7.  The effects of Crocus sativus (saffron) and its constituents on nervous system: A review.

Authors:  Mohammad Reza Khazdair; Mohammad Hossein Boskabady; Mahmoud Hosseini; Ramin Rezaee; Aristidis M Tsatsakis
Journal:  Avicenna J Phytomed       Date:  2015 Sep-Oct

8.  Crocus sativus L. (Saffron) extract and its active constituents (crocin and safranal) on ischemia-reperfusion in rat skeletal muscle.

Authors:  Hossein Hosseinzadeh; Mohammad Hadi Modaghegh; Zahra Saffari
Journal:  Evid Based Complement Alternat Med       Date:  2007-10-25       Impact factor: 2.629

9.  Effect of Aqueous Extract of Crocus sativus L. on Morphine-Induced Memory Impairment.

Authors:  Sayede Maryam Naghibi; Mahmoud Hosseini; Fatemeh Khani; Motahare Rahimi; Farzaneh Vafaee; Hassan Rakhshandeh; Azita Aghaie
Journal:  Adv Pharmacol Sci       Date:  2012-10-10

10.  Effects of Saffron (Crocus sativus L.) Aqueous Extract on In vitro Maturation, Fertilization and Embryo Development of Mouse Oocytes.

Authors:  Somayeh Tavana; Hussein Eimani; Mahnaz Azarnia; Abdolhossein Shahverdi; Poopak Eftekhari-Yazdi
Journal:  Cell J       Date:  2011-12-22       Impact factor: 2.479
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