Literature DB >> 10642416

Qualitative assessment of isocyanate skin exposure in auto body shops: a pilot study.

Y Liu1, J Sparer, S R Woskie, M R Cullen, J S Chung, C T Holm, C A Redlich.   

Abstract

BACKGROUND: Little is known about the extent of human isocyanate skin exposure in auto body shops and the effectiveness of personal protective equipment. Animal studies have suggested that skin exposure to isocyanates may be an important risk factor for respiratory sensitization leading to asthma. This study provides initial data on hexamethylene diisocyanate skin exposure in three auto body shops.
METHODS: Three auto body shops of different size which use different paint systems were examined for the presence of aliphatic isocyanates on environmental surfaces and workers' skin and for breakthrough of personal protective equipment. Qualitative detection of contamination by isocyanates was conducted using a wipe-sampling technique. Assessment focused on the painters and their tasks, although other auto body repairers were also evaluated.
RESULTS: Environmental surfaces such as painters' workbenches, spray equipment, and cleaning tools were found contaminated with isocyanates. Painters had frequent contact with contaminated surfaces, often without wearing gloves. Moderate to heavy contamination of some skin surfaces was found with painters from two of the three auto body shops. Latex gloves used for skin protection showed significant penetrations by isocyanates even after a single painting session.
CONCLUSIONS: Contaminated environmental surfaces and skin exposure to isocyanates were documented in several auto body shops. Latex gloves were not adequate protection for workers using isocyanate paints. Further research which would better quantify skin exposure, and its potential relationship to respiratory sensitization and asthma is warranted. Copyright 2000 Wiley-Liss, Inc.

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Year:  2000        PMID: 10642416     DOI: 10.1002/(sici)1097-0274(200003)37:3<265::aid-ajim4>3.0.co;2-o

Source DB:  PubMed          Journal:  Am J Ind Med        ISSN: 0271-3586            Impact factor:   2.214


  9 in total

1.  Dermal, inhalation, and internal exposure to 1,6-HDI and its oligomers in car body repair shop workers and industrial spray painters.

Authors:  A Pronk; F Yu; J Vlaanderen; E Tielemans; L Preller; I Bobeldijk; J A Deddens; U Latza; X Baur; D Heederik
Journal:  Occup Environ Med       Date:  2006-05-25       Impact factor: 4.402

2.  Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: III. A personal exposure algorithm.

Authors:  Youcheng Liu; Meredith H Stowe; Dhimiter Bello; Judy Sparer; Rebecca J Gore; Mark R Cullen; Carrie A Redlich; Susan R Woskie
Journal:  Ann Occup Hyg       Date:  2008-11-14

3.  Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: initial one-year follow-up.

Authors:  Wei Gui; Adam V Wisnewski; Iulia Neamtiu; Eugen Gurzau; Judith A Sparer; Meredith H Stowe; Jian Liu; Martin D Slade; Olivia A Rusu; Carrie A Redlich
Journal:  Am J Ind Med       Date:  2014-09-29       Impact factor: 2.214

4.  Migration of Beryllium via Multiple Exposure Pathways among Work Processes in Four Different Facilities.

Authors:  Jenna L Armstrong; Gregory A Day; Ji Young Park; Aleksandr B Stefaniak; Marcia L Stanton; David C Deubner; Michael S Kent; Christine R Schuler; M Abbas Virji
Journal:  J Occup Environ Hyg       Date:  2014       Impact factor: 2.155

5.  Review of the occupational exposure to isocyanates: Mechanisms of action.

Authors:  Kazuko Nakashima; Tatsuya Takeshita; Kanehisa Morimoto
Journal:  Environ Health Prev Med       Date:  2002-04       Impact factor: 3.674

6.  Quantification and statistical modeling--part II: dermal concentrations of monomeric and polymeric 1,6-hexamethylene diisocyanate.

Authors:  Kenneth W Fent; Linda G Trelles Gaines; Jennifer M Thomasen; Sheila L Flack; Kai Ding; Amy H Herring; Stephen G Whittaker; Leena A Nylander-French
Journal:  Ann Occup Hyg       Date:  2009-07-27

Review 7.  Skin exposure to isocyanates: reasons for concern.

Authors:  Dhimiter Bello; Christina A Herrick; Thomas J Smith; Susan R Woskie; Robert P Streicher; Mark R Cullen; Youcheng Liu; Carrie A Redlich
Journal:  Environ Health Perspect       Date:  2006-11-28       Impact factor: 9.031

8.  Residual Isocyanates in Medical Devices and Products: A Qualitative and Quantitative Assessment.

Authors:  Gillian Franklin; Homero Harari; Samavi Ahsan; Dhimiter Bello; David A Sterling; Jonathan Nedrelow; Scott Raynaud; Swati Biswas; Youcheng Liu
Journal:  Environ Health Insights       Date:  2016-10-13

9.  A case of isocyanate-induced asthma possibly complicated by food allergy after peanut consumption: a case report.

Authors:  Ervin C Mingomataj; Enkelejda Gjata; Fatmira Xhixha; Entela Hyso
Journal:  J Occup Med Toxicol       Date:  2008-11-26       Impact factor: 2.646

  9 in total

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