Literature DB >> 10642053

Malignant fibrous histiocytoma of the scalp. Multidisciplinary treatment.

F M Camacho1, J C Moreno, M Murga, J Proaño, J Cantillana, M Naranjo, A Martínez-Sahuquillo, G Macher, F Romero.   

Abstract

BACKGROUND: Malignant fibrous histiocytomas (MFH) are uncommon in the skin, and even less frequent on the scalp. On the scalp they are often very difficult to excise and it is even more difficult to close the resulting wound.
OBJECTIVE: To review all malignant fibrous histiocytomas diagnosed and treated in our Department during the past 6 years, and to describe the multidisciplinary procedure employed to treat one special case of aggressive malignant fibrous histiocytoma on the scalp that recurred twice. RESULT: Malignant fibrous histiocytomas represent 0.01% of malignant cutaneous tumors in our area. The immediate results after a multidisciplinary treatment performed on a recurrent malignant fibrous histiocytoma located on the scalp were excellent, but recurrence was observed 6 months later. Two years later we have also treated another case of MFH on the scalp. The same surgical technique was performed, but the patient received high-dose-methotrexate-based neoadjuvant chemotherapy (HD-MTX). One year later, this patient is still alive and no signs of recurrence have been detected.
CONCLUSION: When malignant fibrous histiocytoma occurs on the scalp it must be treated immediately by means of an excision with a large peripheral edge of 2 cm from the visual or CAT limits of the lesion, since the first treatment must be definitive.

Entities:  

Mesh:

Substances:

Year:  1999        PMID: 10642053

Source DB:  PubMed          Journal:  J Eur Acad Dermatol Venereol        ISSN: 0926-9959            Impact factor:   6.166


  1 in total

1.  Malignant Fibrous Histiocytoma of the Scalp with Skull Invasion: A Rare and Aggressive Presentation.

Authors:  Peter Andrawes; David A Hill; Marilyn Ng; Ami Raval; Alfred Culliford
Journal:  Cureus       Date:  2020-04-23
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.