Literature DB >> 10640281

Neuronal nicotinic acetylcholine receptors as novel drug targets.

G K Lloyd1, M Williams.   

Abstract

Mesh：

Substances：

Year:  2000        PMID： 10640281

Source DB:  PubMed          Journal:  J Pharmacol Exp Ther        ISSN： 0022-3565            Impact factor:   4.030


× No keyword cloud information.
  55 in total

1.  N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors.

Authors:  Jianhong Chen; Seth Norrholm; Linda P Dwoskin; Peter A Crooks; Donglu Bai
Journal:  Bioorg Med Chem Lett       Date:  2003-01-06       Impact factor: 2.823

2.  Thermodynamic conformational analysis and structural stability of the nicotinic analgesic ABT-594.

Authors:  M Mora; C Muñoz-Caro; A Niño
Journal:  J Comput Aided Mol Des       Date:  2003-11       Impact factor: 3.686

3.  Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors.

Authors:  Brandon J Henderson; Ryan E Pavlovicz; Jerad D Allen; Tatiana F González-Cestari; Crina M Orac; Andrew B Bonnell; Michael X Zhu; R Thomas Boyd; Chenglong Li; Stephen C Bergmeier; Dennis B McKay
Journal:  J Pharmacol Exp Ther       Date:  2010-06-15       Impact factor: 4.030

Review 4.  From smoking to lung cancer: the CHRNA5/A3/B4 connection.

Authors:  M R D Improgo; M D Scofield; A R Tapper; P D Gardner
Journal:  Oncogene       Date:  2010-06-28       Impact factor: 9.867

5.  Quantitative Molecular Imaging of Neuronal Nicotinic Acetylcholine Receptors in the Human Brain with A-85380 Radiotracers.

Authors:  Shahrdad Lotfipour; Mark Mandelkern; Arthur L Brody
Journal:  Curr Med Imaging Rev       Date:  2011-05-01

6.  3D-QSAR and 3D-QSSR models of negative allosteric modulators facilitate the design of a novel selective antagonist of human α4β2 neuronal nicotinic acetylcholine receptors.

Authors:  Brandon J Henderson; Crina M Orac; Iwona Maciagiewicz; Stephen C Bergmeier; Dennis B McKay
Journal:  Bioorg Med Chem Lett       Date:  2011-11-20       Impact factor: 2.823

7.  Structure-activity relationship studies of sulfonylpiperazine analogues as novel negative allosteric modulators of human neuronal nicotinic receptors.

Authors:  Brandon J Henderson; Daniel J Carper; Tatiana F González-Cestari; Bitna Yi; Kiran Mahasenan; Ryan E Pavlovicz; Martin L Dalefield; Robert S Coleman; Chenglong Li; Dennis B McKay
Journal:  J Med Chem       Date:  2011-11-18       Impact factor: 7.446

8.  A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptor.

Authors:  Richard J Law; Richard H Henchman; J Andrew McCammon
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-27       Impact factor: 11.205

9.  Synthesis and pharmacological evaluation of novel 9- and 10-substituted cytisine derivatives. Nicotinic ligands of enhanced subtype selectivity.

Authors:  Sheela K Chellappan; Yingxian Xiao; Werner Tueckmantel; Kenneth J Kellar; Alan P Kozikowski
Journal:  J Med Chem       Date:  2006-05-04       Impact factor: 7.446

Review 10.  Nicotinic agonists, antagonists, and modulators from natural sources.

Authors:  John W Daly
Journal:  Cell Mol Neurobiol       Date:  2005-06       Impact factor: 5.046
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.