Literature DB >> 1064018

Characterization of a gamma-carboxyglutamic acid-containing protein from bone.

P A Price, A A Otsuka, J W Poser, J Kristaponis, N Raman.   

Abstract

A gamma-carboxyglutamic acid-containing protein has been purified from the calcified tissues of several vertebrates. The presence of three-gamma-carboxyglutamic acid residues in the bovine protein was established by alkaline hydrolysis and amino acid analysis, a method based upon studies with synthetic gamma-carboxyglutamic acid. The identity of gamma-carboxyglutamic acid in the bovine protein was established by mass spectroscopy on the unknown amino acid isolated from alkaline hydrolysates.

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Year:  1976        PMID: 1064018      PMCID: PMC430313          DOI: 10.1073/pnas.73.5.1447

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  13 in total

1.  Atomic structure of intracellular amorphous calcium phosphate deposits.

Authors:  F Betts; N C Blumenthal; A S Posner; G L Becker; A L Lehninger
Journal:  Proc Natl Acad Sci U S A       Date:  1975-06       Impact factor: 11.205

2.  Bovine factor X1 (Stuart factor). Primary structure of the light chain.

Authors:  D L Enfield; L H Ericsson; K A Walsh; H Neurath; K Titani
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

3.  Determination of the tryptophan content of proteins by ion exchange chromatography of alkaline hydrolysates.

Authors:  T E Hugli; S Moore
Journal:  J Biol Chem       Date:  1972-05-10       Impact factor: 5.157

4.  Primary structure of the vitamin K-dependent part of prothrombin.

Authors:  S Magnusson; L Sottrup-Jensen; T E Petersen; H R Morris; A Dell
Journal:  FEBS Lett       Date:  1974-08-25       Impact factor: 4.124

5.  The mode of action of vitamin K. Identification of gamma-carboxyglutamic acid as a component of prothrombin.

Authors:  G L Nelsestuen; T H Zytkovicz; J B Howard
Journal:  J Biol Chem       Date:  1974-10-10       Impact factor: 5.157

6.  Purification and partial characterization of human and porcine C3a anaphylatoxin.

Authors:  T E Hugli; E H Vallota; H J Müller-Eberhard
Journal:  J Biol Chem       Date:  1975-02-25       Impact factor: 5.157

7.  Vitamin K dependent modifications of glutamic acid residues in prothrombin.

Authors:  J Stenflo; P Fernlund; W Egan; P Roepstorff
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

8.  A polypeptide region of bovine prothrombin specific for binding to phospholipids.

Authors:  S N Gitel; W G Owen; C T Esmon; C M Jackson
Journal:  Proc Natl Acad Sci U S A       Date:  1973-05       Impact factor: 11.205

9.  Bone morphogenesis in implants of insoluble bone gelatin.

Authors:  M R Urist; H Iwata; P L Ceccotti; R L Dorfman; S D Boyd; R M McDowell; C Chien
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

10.  Direct identification of the calcium-binding amino acid, gamma-carboxyglutamate, in mineralized tissue.

Authors:  P V Hauschka; J B Lian; P M Gallop
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

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  175 in total

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Authors:  Hankui Chen; Kevin Kolman; Natalie Lanciloti; Michael Nerney; Emily Hays; Chet Robson; Nalini Chandar
Journal:  Exp Cell Res       Date:  2012-03-03       Impact factor: 3.905

2.  Effects of a short course of oral phosphate treatment on serum parathyroid hormone(1-84) and biochemical markers of bone turnover: a dose-response study.

Authors:  K Brixen; H K Nielsen; P Charles; L Mosekilde
Journal:  Calcif Tissue Int       Date:  1992-10       Impact factor: 4.333

3.  Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins.

Authors:  G K Hunter; P V Hauschka; A R Poole; L C Rosenberg; H A Goldberg
Journal:  Biochem J       Date:  1996-07-01       Impact factor: 3.857

Review 4.  An overview of osteocalcin progress.

Authors:  Jinqiao Li; Hongyu Zhang; Chao Yang; Yinghui Li; Zhongquan Dai
Journal:  J Bone Miner Metab       Date:  2016-01-08       Impact factor: 2.626

5.  Primary structure of the gamma-carboxyglutamic acid-containing protein from bovine bone.

Authors:  P A Price; J W Poser; N Raman
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

6.  Ultrastructural localization of osteocalcin in rat tooth germs by immunogold staining.

Authors:  I Gorter de Vries; D Coomans; E Wisse
Journal:  Histochemistry       Date:  1988

7.  Osteoblasts mediate the adverse effects of glucocorticoids on fuel metabolism.

Authors:  Tara C Brennan-Speranza; Holger Henneicke; Sylvia J Gasparini; Katharina I Blankenstein; Uta Heinevetter; Victoria C Cogger; Dmitri Svistounov; Yaqing Zhang; Gregory J Cooney; Frank Buttgereit; Colin R Dunstan; Caren Gundberg; Hong Zhou; Markus J Seibel
Journal:  J Clin Invest       Date:  2012-10-24       Impact factor: 14.808

8.  Identification of the noncollagenous proteins of bovine bone by two-dimensional gel electrophoresis.

Authors:  P D Delmas; R P Tracy; B L Riggs; K G Mann
Journal:  Calcif Tissue Int       Date:  1984-05       Impact factor: 4.333

9.  Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene.

Authors:  Mamoru Igarashi; Yoshiko Yogiashi; Masatomo Mihara; Ichiro Takada; Hirochika Kitagawa; Shigeaki Kato
Journal:  Mol Cell Biol       Date:  2007-09-17       Impact factor: 4.272

10.  Conformational changes of bovine bone osteonectin induced by interaction with calcium.

Authors:  H Takita; Y Kuboki
Journal:  Calcif Tissue Int       Date:  1995-06       Impact factor: 4.333

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