| Literature DB >> 10637486 |
M Bernard1, F Lemée, F Picard, C Ghandour, B Drenou, P Y Le Prise, T Lamy.
Abstract
Jumping translocation (JT) is a very rare cytogenetic event, occurring especially in cancer. We describe a case of secondary acute monocytic leukemia (AML5b) with a JT involving the 3q13-3qter segment and leading to a partial trisomy 3. Each clone with JT was associated with trisomy 8 or tetrasomy 8. The literature of JT in AML cases is reviewed: only 13 cases of AML associated with JT have been previously described, seven of which are AML4/5 FAB subtype. Jumping translocation involvement in leukemogenesis is discussed. Leukemia (2000) 14, 119-122.Entities:
Mesh：
Year: 2000 PMID： 10637486 DOI： 10.1038/sj.leu.2401637
Source DB: PubMed Journal: Leukemia ISSN： 0887-6924 Impact factor: 11.528