Literature DB >> 1063730

A new translocation in chronic myelogenous leukemia.

D Pravtcheva, P Andreeva, R Tsaneva.   

Abstract

A reciprocal translocation involving chromosomes Nos. 3 and 22 has been found in a patient with seemingly Ph-negative chronic myelogenous leukemia (CML). G-band analysis revealed, that deletion in No. 22 occurred at the same point, as in the typical cases of the disease. It was concluded, that breakage in No. 22 at a specific site with spatial disjunction of the resulting segments might be the crucial cytogenetic event in the genesis of CML, the Philadelphia chromosome not being an obligatory result of the rearrangement.

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Year:  1976        PMID: 1063730     DOI: 10.1007/bf00291511

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  9 in total

1.  Two complex translocations in chronic granulocytic leukemia involving chromosomes 22, 9, and a third chromosome.

Authors:  P C Nowell; J Jensen; F Gardner
Journal:  Humangenetik       Date:  1975-10-20

2.  Letter: A new translocation related to the Philadelphia chromosome.

Authors:  I Hayata; S Kakati; A A Sandberg
Journal:  Lancet       Date:  1973-12-15       Impact factor: 79.321

3.  Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.

Authors:  J D Rowley
Journal:  Nature       Date:  1973-06-01       Impact factor: 49.962

4.  Banding in human chromosomes treated with trypsin.

Authors:  H C Wang; S Fedoroff
Journal:  Nat New Biol       Date:  1972-01-12

5.  Letter: Philadelphia chromosome (Ph1) translocation in an apparently Ph1 negative, minus G22, case of chronic myeloid leukemia.

Authors:  E Engel; B J McGee; J M Flexner; M T Russell; B J Myers
Journal:  N Engl J Med       Date:  1974-07-18       Impact factor: 91.245

6.  A new variant translocation (19q plus, 22q minus) in chronic myelocytic leukemia.

Authors:  G Gahrton; L Zech; J Lindsten
Journal:  Exp Cell Res       Date:  1974-05       Impact factor: 3.905

7.  Letter: Another translocation related to the Ph-1 chromosome.

Authors:  I Hayata; S KAKATI; A A Sandberg
Journal:  Lancet       Date:  1975-06-07       Impact factor: 79.321

8.  Experiments with fluorescent chromosome staining in Burkitt tumors.

Authors:  G Manolov; Y Manolova; A Levan; G Klein
Journal:  Hereditas       Date:  1971       Impact factor: 3.271

9.  A new translocation associated with the Ph1 chromosome and an acute course of chronic granulocytic leukaemia.

Authors:  S Muldal; M A Mir; C B Freeman; C G Geary
Journal:  Br J Cancer       Date:  1975-03       Impact factor: 7.640

  9 in total
  4 in total

1.  "Masked" Ph1-chromosome in chronic myelogenous leukaemia (CML).

Authors:  R S Verma; H Dosik
Journal:  Blut       Date:  1985-03

2.  A case of chronic myeloid leukemia with a translocation (12;22)(p13;q11).

Authors:  M van der Blij-Philipsen; W P Breed; T W Hustinx
Journal:  Hum Genet       Date:  1977-11-10       Impact factor: 4.132

3.  Nonrandom chromosome rearrangements in 27 cases of human myeloid leukemia.

Authors:  D Roźynkowa; J Stepień; J Kowalewski; A Nowakowski
Journal:  Hum Genet       Date:  1977-12-23       Impact factor: 4.132

4.  Chronic myelogenous leukemia with translocations (3q-;9q+) and (17q-;22q+). Possible crucial cytogenetic events in the genesis of CML.

Authors:  M Oshimura; K Ohyashiki; M Vehara; Y Miyasaka; S Osamura; A Tonomura
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

  4 in total

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