Literature DB >> 10636161

Botulinum toxin A as treatment for drooling saliva in PD.

P K Pal1, D B Calne, S Calne, J K Tsui.   

Abstract

The authors evaluated intraparotid injections of botulinum toxin A in reducing salivary secretions and drooling in nine patients with PD. There was a marked objective reduction in secretion, and two thirds of the patients had subjective improvement in drooling. No side effects were observed. The authors conclude that botulinum toxin A promises to be a simple and effective treatment for the common problem of drooling saliva in chronic neurologic disease.

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Year:  2000        PMID: 10636161     DOI: 10.1212/wnl.54.1.244

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  24 in total

1.  Treatment of dysautonomia in extrapyramidal disorders.

Authors:  Tjalf Ziemssen; Heinz Reichmann
Journal:  Ther Adv Neurol Disord       Date:  2010-01       Impact factor: 6.570

Review 2.  Is injection of botulinum toxin type A effective in the treatment of drooling in children with cerebral palsy?

Authors:  L Vaile; F Finlay
Journal:  Arch Dis Child       Date:  2006-10       Impact factor: 3.791

Review 3.  Evidence for the effectiveness of botulinum toxin for sialorrhoea.

Authors:  D D Truong; R Bhidayasiri
Journal:  J Neural Transm (Vienna)       Date:  2008-02-04       Impact factor: 3.575

4.  Botulinum toxin therapy: its use for neurological disorders of the autonomic nervous system.

Authors:  Dirk Dressler
Journal:  J Neurol       Date:  2012-08-10       Impact factor: 4.849

Review 5.  Treatment of dysautonomia in extrapyramidal disorders.

Authors:  Tjalf Ziemssen; Gerd Fuchs; Wolfgang Greulich; Heinz Reichmann; Michael Schwarz; Birgit Herting
Journal:  J Neurol       Date:  2011-05       Impact factor: 4.849

Review 6.  Drooling in Parkinson's disease: a review.

Authors:  Prachaya Srivanitchapoom; Sanjay Pandey; Mark Hallett
Journal:  Parkinsonism Relat Disord       Date:  2014-08-27       Impact factor: 4.891

7.  Botulinum toxin: a novel therapy for clozapine-induced sialorrhoea.

Authors:  Rohit Verma; Kuljeet Singh Anand
Journal:  Psychopharmacology (Berl)       Date:  2017-12-01       Impact factor: 4.530

Review 8.  [Treatment of sialorrhea with botulinum toxin: an overview].

Authors:  J Hagenah; K G Kahl; S Steinlechner; R Lencer; C Klein
Journal:  Nervenarzt       Date:  2005-04       Impact factor: 1.214

Review 9.  [Pharmacological strategies for clozapine-induced hypersalivation: treatment with botulinum toxin B in one patient and review of the literature].

Authors:  K G Kahl; P Trillenberg; A Kordon; R Lencer; C Klein; J Hagenah
Journal:  Nervenarzt       Date:  2005-02       Impact factor: 1.214

10.  Botulinum toxin type-B improves sialorrhea and quality of life in bulbaronset amyotrophic lateral sclerosis.

Authors:  João Costa; Maria Luz Rocha; Joaquim Ferreira; Teresinha Evangelista; Miguel Coelho; Mamede de Carvalho
Journal:  J Neurol       Date:  2008-02-19       Impact factor: 4.849

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