Literature DB >> 10635545

Exposure to fungicides in fruit growing: re-entry time as a predictor for dermal exposure.

E Tielemans1, E Louwerse, J de Cock, D Brouwer, G Zielhuis, D Heederik.   

Abstract

As part of a European Concerted Action on Male Reproduction Capability an exposure assessment survey was conducted among seasonal workers in the fruit growing sector in the Netherlands. Dermal exposure to the fungicides captan and tolylfluanid was measured using cotton gloves (12 persons) and skin pads on several body parts (12 persons). In addition, a set of exposure data was used from a study conducted recently among Dutch fruit growers. For harvesting activities, re-entry time appeared to be an important determinant of dermal exposure to captan and tolyfluanid. Explained variance of regression models was moderate to high (range 0.30-0.87). For captan, calculated half-life times from the most recent exposure survey were lower (glove data: 5 days; pad data: 6 days) compared with half-life times based on the previously conducted study (11 days). Possible explanations for the discrepancy are discussed. For tolylfluanid, estimated half-life times during harvesting were 2 and 3 days, based on pad and glove data, respectively. Prediction of captan exposure during other crop activities appeared to be far more difficult (explained variance equal to 0.06), although the estimated half-life time was comparable with that for harvesting. The data suggest that re-entry time gives useful information to group workers in broad exposure categories. Nonetheless, it was concluded that large studies are needed to evaluate the importance of re-entry time in more detail.

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Year:  1999        PMID: 10635545     DOI: 10.1080/00028899908984503

Source DB:  PubMed          Journal:  Am Ind Hyg Assoc J        ISSN: 0002-8894


  10 in total

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4.  Dietary exposure to the endocrine disruptor tolylfluanid promotes global metabolic dysfunction in male mice.

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6.  Induction of SCEs and DNA fragmentation in bovine peripheral lymphocytes by in vitro exposure to tolylfluanid-based fungicide.

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Authors:  Mathilde Bureau; Béatrix Béziat; Geoffroy Duporté; Valérie Bouchart; Yannick Lecluse; Emmanuelle Barron; Alain Garrigou; Marie-Hélène Dévier; Hélène Budzinski; Pierre Lebailly; Isabelle Baldi
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Journal:  J Environ Public Health       Date:  2009-11-05

Review 10.  Association of pesticide exposure with neurologic dysfunction and disease.

Authors:  Freya Kamel; Jane A Hoppin
Journal:  Environ Health Perspect       Date:  2004-06       Impact factor: 9.031

  10 in total

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