Literature DB >> 10633658

Dry eye, blepharitis and chronic eye irritation: divide and conquer.

J P Gilbard1.   

Abstract

Dry eye and posterior blepharitis are the two most common causes for chronic eye irritation. Dry eye is caused by loss of water from the tear film resulting from either decreased tear production or increased tear film evaporation. The resultant increase in tear film osmolarity causes the changes on the eye surface responsible for the symptoms of dry eye. Posterior blepharitis causes eye irritation from inflammation, and leads to the development of meibomian gland dysfunction. The patient history is a powerful tool in narrowing the differential diagnosis of chronic eye irritation or even establishing the diagnosis. The exam adds power to the history, and sorts out the mechanisms causing dry eye symptoms. The primary goal of dry eye treatment is to lower elevated tear film osmolarity. This can be achieved with TheraTears treatment, either with or without punctal plugs. The primary goal of meibomitis treatment is to reduce inflammation. This can be achieved by hot compresses and lid massage and, when necessary, systemic treatment with low dose doxycycline. By determining the cause or causes of chronic eye irritation, effective treatments can be employed.

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Year:  1999        PMID: 10633658

Source DB:  PubMed          Journal:  J Ophthalmic Nurs Technol        ISSN: 0744-7132


  8 in total

Review 1.  Eye complaints in the office environment: precorneal tear film integrity influenced by eye blinking efficiency.

Authors:  P Wolkoff; J K Nøjgaard; P Troiano; B Piccoli
Journal:  Occup Environ Med       Date:  2005-01       Impact factor: 4.402

Review 2.  Dry eye disease: an immune-mediated ocular surface disorder.

Authors:  William Stevenson; Sunil K Chauhan; Reza Dana
Journal:  Arch Ophthalmol       Date:  2012-01

3.  Effects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease.

Authors:  Lili Zhang; Zhitao Su; Zongduan Zhang; Jing Lin; De-Quan Li; Stephen C Pflugfelder
Journal:  JAMA Ophthalmol       Date:  2015-10       Impact factor: 7.389

4.  The role of inflammation and antiinflammation therapies in keratoconjunctivitis sicca.

Authors:  Koray Gumus; Dwight H Cavanagh
Journal:  Clin Ophthalmol       Date:  2009-06-02

5.  [Meibomian glands : part III. Dysfunction - argument for a discrete disease entity and as an important cause of dry eye].

Authors:  E Knop; N Knop; H Brewitt; U Pleyer; P Rieck; B Seitz; F Schirra
Journal:  Ophthalmologe       Date:  2009-11       Impact factor: 1.059

6.  The role of omega-3 dietary supplementation in blepharitis and meibomian gland dysfunction (an AOS thesis).

Authors:  Marian S Macsai
Journal:  Trans Am Ophthalmol Soc       Date:  2008

7.  Irritable bowel syndrome might be associated with dry eye disease.

Authors:  Ioannis Asproudis; Anthoula T Tsoumani; Konstantinos H Katsanos; Aristeidis H Katsanos; Vasileios Theopistos; Konstantinos A Paschidis; Epameinondas V Tsianos; Dimitrios Christodoulou
Journal:  Ann Gastroenterol       Date:  2016-06-16

8.  Tear osmolarity and dry eye symptoms in diabetics.

Authors:  Nicole Fuerst; Nicole Langelier; Mina Massaro-Giordano; Maxwell Pistilli; Kalliopi Stasi; Carrie Burns; Serena Cardillo; Vatinee Y Bunya
Journal:  Clin Ophthalmol       Date:  2014-03-10
  8 in total

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