Literature DB >> 10633035

Discovery of orally active nonpeptide vitronectin receptor antagonists based on a 2-benzazepine Gly-Asp mimetic.

W H Miller1, D P Alberts, P K Bhatnagar, W E Bondinell, J F Callahan, R R Calvo, R D Cousins, K F Erhard, D A Heerding, R M Keenan, C Kwon, P J Manley, K A Newlander, S T Ross, J M Samanen, I N Uzinskas, J W Venslavsky, C C Yuan, R C Haltiwanger, M Gowen, S M Hwang, I E James, M W Lark, D J Rieman, G B Stroup, L M Azzarano, K L Salyers, B R Smith, K W Ward, K O Johanson, W F Huffman.   

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Year:  2000        PMID： 10633035     DOI： 10.1021/jm990446u

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  13 in total

1.  Chemically programmed monoclonal antibodies for cancer therapy: adaptor immunotherapy based on a covalent antibody catalyst.

Authors:  Christoph Rader; Subhash C Sinha; Mikhail Popkov; Richard A Lerner; Carlos F Barbas
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-17       Impact factor: 11.205

Review 2.  Design and implementation of high throughput screening assays.

Authors:  Ricardo Macarrón; Robert P Hertzberg
Journal:  Mol Biotechnol       Date:  2011-03       Impact factor: 2.695

3.  Shear stress induced release of von Willebrand factor and thrombospondin-1 in HUVEC extracellular matrix enhances breast tumour cell adhesion.

Authors:  Noëlia Gomes; Chantal Legrand; Françoise Fauvel-Lafève
Journal:  Clin Exp Metastasis       Date:  2005       Impact factor: 5.150

4.  Development of small molecules designed to modulate protein-protein interactions.

Authors:  Ye Che; Bernard R Brooks; Garland R Marshall
Journal:  J Comput Aided Mol Des       Date:  2006-04-19       Impact factor: 3.686

Review 5.  Chemically programmed antibodies.

Authors:  Christoph Rader
Journal:  Trends Biotechnol       Date:  2014-03-11       Impact factor: 19.536

6.  Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

Authors:  Hyeonwoo Kim; Christiane D Wrann; Mark Jedrychowski; Sara Vidoni; Yukiko Kitase; Kenichi Nagano; Chenhe Zhou; Joshua Chou; Virginia-Jeni A Parkman; Scott J Novick; Timothy S Strutzenberg; Bruce D Pascal; Phuong T Le; Daniel J Brooks; Alexander M Roche; Kaitlyn K Gerber; Laura Mattheis; Wenjing Chen; Hua Tu; Mary L Bouxsein; Patrick R Griffin; Roland Baron; Clifford J Rosen; Lynda F Bonewald; Bruce M Spiegelman
Journal:  Cell       Date:  2018-12-13       Impact factor: 41.582

7.  Spontaneous Extracellular Matrix Accumulation in a Human in vitro Model of Renal Fibrosis Is Mediated by αV Integrins.

Authors:  Hélène Bon; Paul Hales; Simon Lumb; Gill Holdsworth; Tim Johnson; Omar Qureshi; Breda M Twomey
Journal:  Nephron       Date:  2019-05-02       Impact factor: 2.847

8.  Breast adenocarcinoma cell adhesion to the vascular subendothelium in whole blood and under flow conditions: effects of alphavbeta3 and alphaIIbbeta3 antagonists.

Authors:  Noëlia Gomes; Jany Vassy; Claude Lebos; Brigitte Arbeille; Chantal Legrand; Françoise Fauvel-Lafeve
Journal:  Clin Exp Metastasis       Date:  2004       Impact factor: 5.150

9.  SB-273005, an antagonist of αvβ3 integrin, reduces the production of Th2 cells and cytokine IL-10 in pregnant mice.

Authors:  Shaojuan Wang; Jing Yang; Chongyang Wang; Qing Yang; Xiaoli Zhou
Journal:  Exp Ther Med       Date:  2014-04-07       Impact factor: 2.447

10.  A potential peptide vector that allows targeted delivery of a desired fusion protein into the human breast cancer cell line MDA-MB-231.

Authors:  Wei Qing Liu; Jun Yang; Min Hong; Chang E Gao; Jian Dong
Journal:  Oncol Lett       Date:  2016-05-06       Impact factor: 2.967
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