Literature DB >> 10632228

Is depression an adaptation?

R M Nesse1.   

Abstract

Many functions have been suggested for low mood or depression, including communicating a need for help, signaling yielding in a hierarchy conflict, fostering disengagement from commitments to unreachable goals, and regulating patterns of investment. A more comprehensive evolutionary explanation may emerge from attempts to identify how the characteristics of low mood increase an organism's ability to cope with the adaptive challenges characteristic of unpropitious situations in which effort to pursue a major goal will likely result in danger, loss, bodily damage, or wasted effort. In such situations, pessimism and lack of motivation may give a fitness advantage by inhibiting certain actions, especially futile or dangerous challenges to dominant figures, actions in the absence of a crucial resource or a viable plan, efforts that would damage the body, and actions that would disrupt a currently unsatisfactory major life enterprise when it might recover or the alternative is likely to be even worse. These hypotheses are consistent with considerable evidence and suggest specific tests.

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Year:  2000        PMID: 10632228     DOI: 10.1001/archpsyc.57.1.14

Source DB:  PubMed          Journal:  Arch Gen Psychiatry        ISSN: 0003-990X


  101 in total

Review 1.  On the difficulty of defining disease: a Darwinian perspective.

Authors:  R M Nesse
Journal:  Med Health Care Philos       Date:  2001

Review 2.  Natural selection and the elusiveness of happiness.

Authors:  Randolph M Nesse
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2004-09-29       Impact factor: 6.237

Review 3.  Depression as a disease of modernity: explanations for increasing prevalence.

Authors:  Brandon H Hidaka
Journal:  J Affect Disord       Date:  2012-01-12       Impact factor: 4.839

4.  The nature of clinical depression: symptoms, syndromes, and behavior analysis.

Authors:  Jonathan W Kanter; Andrew M Busch; Cristal E Weeks; Sara J Landes
Journal:  Behav Anal       Date:  2008

Review 5.  Linking molecules to mood: new insight into the biology of depression.

Authors:  Vaishnav Krishnan; Eric J Nestler
Journal:  Am J Psychiatry       Date:  2010-09-15       Impact factor: 18.112

Review 6.  An integrative and functional framework for the study of animal emotion and mood.

Authors:  Michael Mendl; Oliver H P Burman; Elizabeth S Paul
Journal:  Proc Biol Sci       Date:  2010-08-04       Impact factor: 5.349

Review 7.  Suicide as a derangement of the self-sacrificial aspect of eusociality.

Authors:  Thomas E Joiner; Melanie A Hom; Christopher R Hagan; Caroline Silva
Journal:  Psychol Rev       Date:  2015-11-02       Impact factor: 8.934

8.  Evolutionary biology: a basic science for psychiatry.

Authors:  Randolph M Nesse
Journal:  World Psychiatry       Date:  2002-02       Impact factor: 49.548

9.  Racial Discrimination, John Henryism, and Depression Among African Americans.

Authors:  Darrell L Hudson; Harold W Neighbors; Arline T Geronimus; James S Jackson
Journal:  J Black Psychol       Date:  2016-05-08

Review 10.  Future antidepressants: what is in the pipeline and what is missing?

Authors:  Fokko J Bosker; Ben H C Westerink; Thomas I F H Cremers; Marjolein Gerrits; Marieke G C van der Hart; Sjoukje D Kuipers; Gieta van der Pompe; Gert J ter Horst; Johan A den Boer; Jakob Korf
Journal:  CNS Drugs       Date:  2004       Impact factor: 5.749

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