Literature DB >> 10632071

In search of new chemical entities with spermicidal and anti-HIV activities.

S Srivastava1, L K Bajpai, S Batra, A P Bhaduri, J P Maikhuri, G Gupta, J D Dhar.   

Abstract

Several compounds belonging to 2-isoxazolines (4,5a-c), isoxazoles (3,6a-c) and 1-amino-1-cycloalkyl-2-substituted phenyl ethanes (16-18,a-e) have been synthesised and found to possess spermicidal activity. Out of these a couple of compounds (5a and 6a) exhibit anti-HIV activity.

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Year:  1999        PMID: 10632071     DOI: 10.1016/s0968-0896(99)00188-1

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  5 in total

1.  Diversity oriented synthesis and IKK inhibition of aminobenzimidazole tethered quinazoline-2,4-diones, thioxoquinazolin-4-ones, benzodiazepine-2,3,5-triones, isoxazoles and isoxazolines.

Authors:  Sureshbabu Dadiboyena; Aïcha Arfaoui; Hassen Amri; F Javier Piedrafita; Adel Nefzi
Journal:  Bioorg Med Chem Lett       Date:  2014-12-08       Impact factor: 2.823

2.  Solid Phase Synthesis of Isoxazole and Isoxazoline-carboxamides via [2+3]-Dipolar Cycloaddition Using Resin-bound Alkynes or Alkenes.

Authors:  Sureshbabu Dadiboyena; Adel Nefzi
Journal:  Tetrahedron Lett       Date:  2012-04-18       Impact factor: 2.415

3.  Isoxazoles from 1,1-Disubstituted Bromoalkenes.

Authors:  Sureshbabu Dadiboyena; Jianping Xu; Ashton T Hamme
Journal:  Tetrahedron Lett       Date:  2007-02-12       Impact factor: 2.415

4.  Design and synthesis of novel isoxazole tethered quinone-amino Acid hybrids.

Authors:  P Ravi Kumar; Manoranjan Behera; M Sambaiah; Venu Kandula; Nagaraju Payili; A Jaya Shree; Satyanarayana Yennam
Journal:  J Amino Acids       Date:  2014-11-19

5.  Isoxazole derivatives as new nitric oxide elicitors in plants.

Authors:  Anca Oancea; Emilian Georgescu; Florentina Georgescu; Alina Nicolescu; Elena Iulia Oprita; Catalina Tudora; Lucian Vladulescu; Marius-Constantin Vladulescu; Florin Oancea; Calin Deleanu
Journal:  Beilstein J Org Chem       Date:  2017-04-06       Impact factor: 2.883

  5 in total

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