| Literature DB >> 10632068 |
S K Chung1, Y U Kwon, Y T Chang, K H Sohn, J H Shin, K H Park, B J Hong, I H Chung.
Abstract
scyllo-Inositol is the all equatorial stereoisomer of myo-inositol. All possible 12 regioisomers of scyllo-inositol phosphate were synthesized for the first time via a scyllo-inositol benzoate intermediate, which was derived from a myo-inositol derivative. The stereoinversion of myo-inositol into scyllo-inositol was accomplished by Mitsunobu reaction of the vicinal cis-diol. The requisite intermediates, scyllo-inositol benzoates were obtained by benzoyl migration or random benzoylation, and phosphorylated to give scyllo-IPn.Entities:
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Year: 1999 PMID： 10632068 DOI： 10.1016/s0968-0896(99)00183-2
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641