Literature DB >> 10631557

Genetic dissection of systemic lupus erythematosus.

E K Wakeland1, A E Wandstrat, K Liu, L Morel.   

Abstract

Recent progress towards elucidating the genetic basis for susceptibility to systemic lupus erythematosus (SLE) has provided insights into the manner in which individual susceptibility genes contribute to disease pathogenesis. Studies in animal models of systemic autoimmunity suggest that genes in three separate pathways contribute to the initiation and progression of systemic autoimmunity. Linkage studies in humans suggest that at least some susceptibility genes mediating disease in lupus-prone mice may also contribute to susceptibility in humans.

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Year:  1999        PMID： 10631557     DOI： 10.1016/s0952-7915(99)00039-4

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  36 in total

Review 1.  Genetics and systemic lupus erythematosus.

Authors:  B P Tsao; J M Grossman
Journal:  Curr Rheumatol Rep       Date:  2001-06       Impact factor: 4.592

2.  Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosus.

Authors:  Aleksandar K Stanic; Charles M Stein; Adam C Morgan; Sergio Fazio; MacRae F Linton; Edward K Wakeland; Nancy J Olsen; Amy S Major
Journal:  Proc Natl Acad Sci U S A       Date:  2006-04-24       Impact factor: 11.205

3.  A genetic lesion that arrests plasma cell homing to the bone marrow.

Authors:  Loren D Erickson; Ling-Li Lin; Biyan Duan; Laurence Morel; Randolph J Noelle
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-10       Impact factor: 11.205

4.  The NZM2410-derived lupus susceptibility locus Sle2c1 increases Th17 polarization and induces nephritis in fas-deficient mice.

Authors:  Zhiwei Xu; Carla M Cuda; Byron P Croker; Laurence Morel
Journal:  Arthritis Rheum       Date:  2011-03

5.  DNase II polymorphisms associated with risk of renal disorder among systemic lupus erythematosus patients.

Authors:  Hyoung Doo Shin; Byung Lae Park; Hyun Sup Cheong; Hye-Soon Lee; Jae-Bum Jun; Sang-Cheol Bae
Journal:  J Hum Genet       Date:  2005-02-19       Impact factor: 3.172

6.  Development of murine lupus involves the combined genetic contribution of the SLAM and FcgammaR intervals within the Nba2 autoimmune susceptibility locus.

Authors:  Trine N Jørgensen; Jennifer Alfaro; Hilda L Enriquez; Chao Jiang; William M Loo; Stephanie Atencio; Melanie R Gubbels Bupp; Christina M Mailloux; Troy Metzger; Shannon Flannery; Stephen J Rozzo; Brian L Kotzin; Mario Rosemblatt; María Rosa Bono; Loren D Erickson
Journal:  J Immunol       Date:  2009-12-16       Impact factor: 5.422

Review 7.  The rise and fall of long-lived humoral immunity: terminal differentiation of plasma cells in health and disease.

Authors:  Brian P O'Connor; Michael W Gleeson; Randolph J Noelle; Loren D Erickson
Journal:  Immunol Rev       Date:  2003-08       Impact factor: 12.988

8.  Identification of gp96 as a novel target for treatment of autoimmune disease in mice.

Authors:  Jung Min Han; Nam Hoon Kwon; Jin Young Lee; Seung Jae Jeong; Hee Jung Jung; Hyeong Rae Kim; Zihai Li; Sunghoon Kim
Journal:  PLoS One       Date:  2010-03-23       Impact factor: 3.240

9.  Regulation of B cell tolerance by 129-derived chromosome 1 loci in C57BL/6 mice.

Authors:  Liliane Fossati-Jimack; Josefina Cortes-Hernandez; Peter J Norsworthy; H Terence Cook; Mark J Walport; Marina Botto
Journal:  Arthritis Rheum       Date:  2008-07

10.  The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis.

Authors:  Q-Z Li; J Zhou; R Yang; M Yan; Q Ye; K Liu; S Liu; X Shao; L Li; X-J Zhou; E K Wakeland; C Mohan
Journal:  Genes Immun       Date:  2009-03-05       Impact factor: 2.676
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