Literature DB >> 10631556

Mapping autoimmunity genes.

M M Griffiths1, J A Encinas, E F Remmers, V K Kuchroo, R L Wilder.   

Abstract

Rat and mouse models for the major human autoimmune/inflammatory diseases are under intense genetic scrutiny. Genome-wide linkage studies reveal that each model is regulated by multiple genetic loci. Many of these loci colocalize to homologous genomic regions associated with several different autoimmune diseases of mice, rats and humans. Candidate genes are being identified. Polymorphic alleles associated with these chromosomal segments may represent predisposing genetic elements common to a number of human diseases with very different clinical presentations.

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Year:  1999        PMID: 10631556     DOI: 10.1016/s0952-7915(99)00038-2

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  19 in total

Review 1.  Science, medicine, and the future: Tolerance and autoimmunity.

Authors:  I R Mackay
Journal:  BMJ       Date:  2000-07-08

2.  Gene-expression profiling of experimental autoimmune encephalomyelitis.

Authors:  Eilhard Mix; Jens Pahnke; Saleh M Ibrahim
Journal:  Neurochem Res       Date:  2002-10       Impact factor: 3.996

3.  Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases.

Authors:  Jin-Hui Tao; Yan-Feng Zou; Xiao-Liang Feng; Jing Li; Fang Wang; Fan-Ming Pan; Dong-Qing Ye
Journal:  Mol Biol Rep       Date:  2010-12-08       Impact factor: 2.316

4.  Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

Authors:  Jian Wang; Taku Yoshida; Fumio Nakaki; Hiroshi Hiai; Taku Okazaki; Tasuku Honjo
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-08       Impact factor: 11.205

5.  Regulation of contact sensitivity in non-obese diabetic (NOD) mice by innate immunity.

Authors:  Marian Szczepanik; Monika Majewska-Szczepanik; Florence S Wong; Paulina Kowalczyk; Chandrashekhar Pasare; Li Wen
Journal:  Contact Dermatitis       Date:  2018-06-25       Impact factor: 6.600

6.  Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat.

Authors:  Xiaojiang Quan; Jean-François Laes; Daniel Stieber; Michèle Rivière; Jose Russo; Dirk Wedekind; Wouter Coppieters; Frédéric Farnir; Michel Georges; Josiane Szpirer; Claude Szpirer
Journal:  Mamm Genome       Date:  2006-04-04       Impact factor: 2.957

7.  CD69 downregulates autoimmune reactivity through active transforming growth factor-beta production in collagen-induced arthritis.

Authors:  David Sancho; Manuel Gómez; Fernando Viedma; Enric Esplugues; Mónica Gordón-Alonso; María Angeles García-López; Hortensia de la Fuente; Carlos Martínez-A; Pilar Lauzurica; Francisco Sánchez-Madrid
Journal:  J Clin Invest       Date:  2003-09       Impact factor: 14.808

8.  Common genetic determinants of uveitis shared with other autoimmune disorders.

Authors:  Mary J Mattapallil; Azize Sahin; Phyllis B Silver; Shu-Hui Sun; Chi-Chao Chan; Elaine F Remmers; J Fielding Hejtmancik; Rachel R Caspi
Journal:  J Immunol       Date:  2008-05-15       Impact factor: 5.422

9.  A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

Authors:  Ann B Begovich; Victoria E H Carlton; Lee A Honigberg; Steven J Schrodi; Anand P Chokkalingam; Heather C Alexander; Kristin G Ardlie; Qiqing Huang; Ashley M Smith; Jill M Spoerke; Marion T Conn; Monica Chang; Sheng-Yung P Chang; Randall K Saiki; Joseph J Catanese; Diane U Leong; Veronica E Garcia; Linda B McAllister; Douglas A Jeffery; Annette T Lee; Franak Batliwalla; Elaine Remmers; Lindsey A Criswell; Michael F Seldin; Daniel L Kastner; Christopher I Amos; John J Sninsky; Peter K Gregersen
Journal:  Am J Hum Genet       Date:  2004-06-18       Impact factor: 11.025

Review 10.  Mammary cancer susceptibility: human genes and rodent models.

Authors:  Claude Szpirer; Josiane Szpirer
Journal:  Mamm Genome       Date:  2007-12-01       Impact factor: 2.957

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