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Literature DB >> 10631555

Apoptotic and effector pathways in autoimmunity.

Abstract

Programmed cell death is an important anti-autoimmune mechanism used to delete autoreactive lymphocytes and to limit the spread both of viral infections and of tissue damage caused by immune responses. However, in autoimmune diseases, activation of programmed cell death by effector mechanisms that are similar to the normal immune response leads to augmented destruction of the targeted tissues.

Entities: Disease

Mesh：

Year: 1999 PMID： 10631555 DOI： 10.1016/s0952-7915(99)00037-0

Source DB: PubMed Journal: Curr Opin Immunol ISSN： 0952-7915 Impact factor: 7.486

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Cited

10 in total

1. Contribution of Fas to diabetes development.

Authors: Alexei Y Savinov; Andrew Tcherepanov; E Allison Green; Richard A Flavell; Alexander V Chervonsky
Journal: Proc Natl Acad Sci U S A Date: 2003-01-13 Impact factor: 11.205

2. Neutralization of interleukin-16 protects nonobese diabetic mice from autoimmune type 1 diabetes by a CCL4-dependent mechanism.

Authors: Craig Meagher; Josh Beilke; Guillermo Arreaza; Qing-Sheng Mi; Wei Chen; Konstantin Salojin; Noah Horst; William W Cruikshank; Terry L Delovitch
Journal: Diabetes Date: 2010-08-06 Impact factor: 9.461

3. Shared molecular and functional frameworks among five complex human disorders: a comparative study on interactomes linked to susceptibility genes.

Authors: Ramesh Menon; Cinthia Farina
Journal: PLoS One Date: 2011-04-21 Impact factor: 3.240

4. Urothelial antigen-specific CD4+ T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8+ T cells.

Authors: W Liu; X Chen; D P Evanoff; Y Luo
Journal: Mucosal Immunol Date: 2011-01-26 Impact factor: 7.313

5. NAPO as a novel marker for apoptosis.

Authors: B S Sayan; G Ince; A E Sayan; M Ozturk
Journal: J Cell Biol Date: 2001-11-19 Impact factor: 10.539

6. FAS-ligand regulates differential activation-induced cell death of human T-helper 1 and 17 cells in healthy donors and multiple sclerosis patients.

Authors: M T Cencioni; S Santini; G Ruocco; G Borsellino; M De Bardi; M G Grasso; S Ruggieri; C Gasperini; D Centonze; D Barilá; L Battistini; E Volpe
Journal: Cell Death Dis Date: 2015-05-07 Impact factor: 8.469

Apoptotic and effector pathways in autoimmunity.

1. Contribution of Fas to diabetes development.

2. Neutralization of interleukin-16 protects nonobese diabetic mice from autoimmune type 1 diabetes by a CCL4-dependent mechanism.

3. Shared molecular and functional frameworks among five complex human disorders: a comparative study on interactomes linked to susceptibility genes.

4. Urothelial antigen-specific CD4+ T cells function as direct effector cells and induce bladder autoimmune inflammation independent of CD8+ T cells.

5. NAPO as a novel marker for apoptosis.

6. FAS-ligand regulates differential activation-induced cell death of human T-helper 1 and 17 cells in healthy donors and multiple sclerosis patients.

Review 7. Fas-Fas Ligand: Checkpoint of T Cell Functions in Multiple Sclerosis.

8. Fas mutation reduces obesity by increasing IL-4 and IL-10 expression and promoting white adipose tissue browning.

9. Genetic polymorphisms and epigenetic regulation of survivin encoding gene, BIRC5, in multiple sclerosis patients.

10. Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity.