Literature DB >> 10630787

Tick-borne encephalitis virus NS3 gene expression does not protect mice from homologous viral challenge.

O V Morozova1, T G Maksimova, V N Bakhvalova.   

Abstract

Tick-borne encephalitis virus (TBEV) NS3 gene has been subcloned into the expression vector pcDNAI and expressed in eukaryotic cells. Immunization of mice with the recombinant plasmid pcDNAI-NS3 induced antibodies against NS3 protein but did not protect from viral challenge.

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Year:  1999        PMID： 10630787     DOI： 10.1089/vim.1999.12.277

Source DB:  PubMed          Journal:  Viral Immunol        ISSN： 0882-8245            Impact factor:   2.257


  4 in total

1.  Genetic vaccination of mice with plasmids encoding the NS1 non-structural protein from tick-borne encephalitis virus and dengue 2 virus.

Authors:  A V Timofeev; V M Butenko; J R Stephenson
Journal:  Virus Genes       Date:  2004-01       Impact factor: 2.332

2.  Induction of a protective response in mice by the dengue virus NS3 protein using DNA vaccines.

Authors:  Simone M Costa; Anna Paula Yorio; Antônio J S Gonçalves; Mariana M Vidale; Emmerson C B Costa; Ronaldo Mohana-Borges; Marcia A Motta; Marcos S Freire; Ada M B Alves
Journal:  PLoS One       Date:  2011-10-21       Impact factor: 3.240

3.  Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3.

Authors:  M L Hurtado-Melgoza; A Ramos-Ligonio; L M Álvarez-Rodríguez; T Meza-Menchaca; A López-Monteon
Journal:  J Biomed Sci       Date:  2016-12-01       Impact factor: 8.410

4.  Recombinant Dengue 2 Virus NS3 Helicase Protein Enhances Antibody and T-Cell Response of Purified Inactivated Vaccine.

Authors:  Monika Simmons; Peifang Sun; Robert Putnak
Journal:  PLoS One       Date:  2016-04-01       Impact factor: 3.240
  4 in total

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