Literature DB >> 10630598

Conjugated linoleic acid and the control of cancer and obesity.

M W Pariza1, Y Park, M E Cook.   

Abstract

The effects of conjugated linoleic acid (CLA) in animals are reviewed. In most of the CLA preparations that have been investigated to date for biological activity, two CLA isomers are present in about equal concentrations: cis-9,trans-11 CLA, and trans-10,cis-12 CLA. The occurrence of these isomers in foods and their production by rumen microorganisms are discussed. Potential mechanisms of action as regards the effects of CLA on cancer and body composition are reviewed, including recent evidence that body composition changes are produced by the trans-10,cis-12 CLA isomer. Evidence is presented indicating that CLA may modulate cellular response to tumor necrosis factor-alpha (TNF-alpha). The mechanistic implications of this finding are considered.

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Year:  1999        PMID： 10630598     DOI： 10.1093/toxsci/52.suppl_1.107

Source DB:  PubMed          Journal:  Toxicol Sci        ISSN： 1096-0929            Impact factor:   4.849


  20 in total

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Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.099

2.  Lung injury-induced skeletal muscle wasting in aged mice is linked to alterations in long chain fatty acid metabolism.

Authors:  D Clark Files; Amro Ilaiwy; Traci L Parry; Kevin W Gibbs; Chun Liu; James R Bain; Osvaldo Delbono; Michael J Muehlbauer; Monte S Willis
Journal:  Metabolomics       Date:  2016-07-26       Impact factor: 4.290

Review 3.  ISSN exercise & sports nutrition review update: research & recommendations.

Authors:  Chad M Kerksick; Colin D Wilborn; Michael D Roberts; Abbie Smith-Ryan; Susan M Kleiner; Ralf Jäger; Rick Collins; Mathew Cooke; Jaci N Davis; Elfego Galvan; Mike Greenwood; Lonnie M Lowery; Robert Wildman; Jose Antonio; Richard B Kreider
Journal:  J Int Soc Sports Nutr       Date:  2018-08-01       Impact factor: 5.150

4.  Identification and analysis of a gene from Calendula officinalis encoding a fatty acid conjugase.

Authors:  X Qiu; D W Reed; H Hong; S L MacKenzie; P S Covello
Journal:  Plant Physiol       Date:  2001-02       Impact factor: 8.340

5.  Meat quality of light lambs is more affected by the dam's feeding system during lactation than by the inclusion of quebracho in the fattening concentrate.

Authors:  S Lobón; M Blanco; A Sanz; G Ripoll; J R Bertolín; M Joy
Journal:  J Anim Sci       Date:  2017-11       Impact factor: 3.159

6.  Inhibitory effects of c9, t11-conjugated linoleic acid on invasion of human gastric carcinoma cell line SGC-7901.

Authors:  Bing-Qing Chen; Yan-Mei Yang; Yan-Hui Gao; Jia-Ren Liu; Ying-Ben Xue; Xuan-Lin Wang; Yu-Mei Zheng; Jing-Shu Zhang; Rui-Hai Liu
Journal:  World J Gastroenterol       Date:  2003-09       Impact factor: 5.742

7.  Effect of the feeding system on the fatty acid composition, expression of the Delta9-desaturase, Peroxisome Proliferator-Activated Receptor Alpha, Gamma, and Sterol Regulatory Element Binding Protein 1 genes in the semitendinous muscle of light lambs of the Rasa Aragonesa breed.

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8.  Effects of c9,t11-conjugated linoleic acid on adhesion of human gastric carcinoma cell line SGC-7901.

Authors:  Bing-Qing Chen; Yan-Mei Yang; Qi Wang; Yan-Hui Gao; Jia-Ren Liu; Jing-Shu Zhang; Xuan-Lin Wang; Rui-Hai Liu
Journal:  World J Gastroenterol       Date:  2004-05-15       Impact factor: 5.742

9.  Dietary protein modulates the effect of CLA on lipid metabolism in rats.

Authors:  Asuka Akahoshi; Kazunori Koba; Fumika Ichinose; Mai Kaneko; Asako Shimoda; Kikuko Nonaka; Masao Yamasaki; Toshio Iwata; Yoshie Yamauchi; Kentaro Tsutsumi; Michihiro Sugano
Journal:  Lipids       Date:  2004-01       Impact factor: 1.880

10.  Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid.

Authors:  Eva Rosberg-Cody; Mark C Johnson; Gerald F Fitzgerald; Paul R Ross; Catherine Stanton
Journal:  Microbiology (Reading)       Date:  2007-08       Impact factor: 2.777
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