Literature DB >> 10630273

Oral frostbite injury from intentional abuse of a fluorinated hydrocarbon.

D A Kuspis1, E P Krenzelok.   

Abstract

BACKGROUND: A serious but rarely reported complication of halogenated hydrocarbon inhalation abuse is severe mucosal frostbite. CASE REPORT: A 16-year-old male attempted to "get high" by inhaling airbrush propellant which contained 1,1-difluoroethane (CAS #75-376). The patient lost consciousness and upon awakening his lips and tongue were frozen. He suffered first- and second-degree burns of the larynx with vocal cord involvement and first-degree burns of the trachea, main stem bronchi, and esophagus. The oral cavity had second- and third-degree burns which required debridement.
CONCLUSION: This case demonstrates the unusual but severe damage that can occur with the abuse of fluorinated hydrocarbons.

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Year:  1999        PMID: 10630273     DOI: 10.1081/clt-100102469

Source DB:  PubMed          Journal:  J Toxicol Clin Toxicol        ISSN: 0731-3810


  3 in total

Review 1.  Volatile substance misuse: an updated review of toxicity and treatment.

Authors:  Jonathan B Ford; Mark E Sutter; Kelly P Owen; Timothy E Albertson
Journal:  Clin Rev Allergy Immunol       Date:  2014-02       Impact factor: 8.667

2.  Inhaling Difluoroethane Computer Cleaner Resulting in Acute Kidney Injury and Chronic Kidney Disease.

Authors:  Kristen Calhoun; Laura Wattenbarger; Ethan Burns; Courtney Hatcher; Amol Patel; Manjulatha Badam; Abdul-Jabbar Khan
Journal:  Case Rep Nephrol       Date:  2018-06-07

3.  1,1-Difluoroethane Detection Time in Blood after Inhalation Abuse Estimated by Monte Carlo PBPK Modeling.

Authors:  Raul Huet; Gunnar Johanson
Journal:  Pharmaceutics       Date:  2020-10-20       Impact factor: 6.321

  3 in total

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