Literature DB >> 10630117

New triterpenoids with antibacterial activity from Zizyphus joazeiro.

W Schühly1, J Heilmann, I Calis, O Sticher.   

Abstract

The stem bark of the Brazilian medicinal plant Zizyphus joazeiro C. Mart. was phytochemically investigated. Three known compounds (betulinic, ursolic and alphitolic acid) and three new derivatives of betulinic acid, 7 beta-(4-hydroxybenzoyloxy)-betulinic acid, 7 beta-(4-hydroxy-3'-methoxybenzoyloxy)-betulinic acid and 27-(4-hydroxy-3'-methoxybenzoyloxy)-betulinic acid which showed a considerable activity against Gram-positive bacteria were isolated from the dichloromethane extract. The structures were established on the basis of NMR spectroscopy and mass spectrometry.

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Year:  1999        PMID: 10630117     DOI: 10.1055/s-1999-14054

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  16 in total

1.  Hypericum species in the Páramos of Central and South America: a special focus upon H. irazuense Kuntze ex N. Robson.

Authors:  Sara Crockett; Marianne Eberhardt; Olaf Kunert; Wolfgang Schühly
Journal:  Phytochem Rev       Date:  2010-06       Impact factor: 5.374

2.  Immunomodulatory effects of betulinic acid from the bark of white birch on mice.

Authors:  Jin-e Yi; Bozena Obminska-Mrukowicz; Li-yun Yuan; Hui Yuan
Journal:  J Vet Sci       Date:  2010-12       Impact factor: 1.672

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Authors:  Kyoko Nakagawa-Goto; Koji Yamada; Masahiko Taniguchi; Harukuni Tokuda; Kuo-Hsiung Lee
Journal:  Bioorg Med Chem Lett       Date:  2009-05-18       Impact factor: 2.823

4.  Safety evaluation of a new anxiolytic product containing botanicals Souroubea spp. and Platanus spp. in dogs.

Authors:  Aleksandar Masic; Rui Liu; Kristen Simkus; Jeff Wilson; John Baker; Pablo Sanchez; Ammar Saleem; Cory C Harris; Tony Durst; John T Arnason
Journal:  Can J Vet Res       Date:  2018-01       Impact factor: 1.310

5.  Betulinic acid protects against N-nitrosodimethylamine-induced redox imbalance in testes of rats.

Authors:  Gbadebo E Adeleke; Oluwatosin A Adaramoye
Journal:  Redox Rep       Date:  2017-05-05       Impact factor: 4.412

6.  Transcriptional profiles of the response of methicillin-resistant Staphylococcus aureus to pentacyclic triterpenoids.

Authors:  Pooi Yin Chung; Lip Yong Chung; Parasakthi Navaratnam
Journal:  PLoS One       Date:  2013-02-20       Impact factor: 3.240

7.  Improvement of betulinic acid biosynthesis in yeast employing multiple strategies.

Authors:  Chen Zhou; Jing Li; Changfu Li; Yansheng Zhang
Journal:  BMC Biotechnol       Date:  2016-08-17       Impact factor: 2.563

8.  Determination of the maximum inhibitory dilution of cetylpyridinium chloride-based mouthwashes against Staphylococcus aureus: an in vitro study.

Authors:  Evandro Watanabe; Juliane Maria Guerreiro Tanomaru; Andresa Piacezzi Nascimento; Fumio Matoba-Júnior; Mario Tanomaru-Filho; Izabel Yoko Ito
Journal:  J Appl Oral Sci       Date:  2008 Jul-Aug       Impact factor: 2.698

9.  Evaluation and optimization of downstream process parameters for extraction of betulinic acid from the bark of Ziziphus jujubae L.

Authors:  Kashyap Kumar Dubey; Nitika Goel
Journal:  ScientificWorldJournal       Date:  2013-11-13

10.  Evaluation of the mutagenicity and antimutagenicity of Ziziphus joazeiro Mart. bark in the micronucleus assay.

Authors:  Marcelo Fabiano Gomes Boriollo; Marielly Reis Resende; Thaísla Andrielle da Silva; Juliana Yoshida Públio; Luiz Silva Souza; Carlos Tadeu Dos Santos Dias; Nelma de Mello Silva Oliveira; João Evangelista Fiorini
Journal:  Genet Mol Biol       Date:  2014-06       Impact factor: 1.771

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