Literature DB >> 10629482

Tonsillectomy in diagnosis of the unknown primary tumor of the head and neck.

D A Randall1, P A Johnstone, R D Foss, P J Martin.   

Abstract

OBJECTIVES: The purpose of this study was to discuss the experience of one tumor registry with performing tonsillectomy in the diagnostic approach to unknown head and neck primary tumors. It also describes the importance of including tonsillectomy in this evaluation algorithm. STUDY
DESIGN: A retrospective chart review was done of 68 patients with either tonsillar or unknown primary squamous cell carcinoma culled from 829 patients seen from 1956 to 1996 at the head and neck tumor registry at the Naval Medical Center San Diego.
METHODS: Records from the head and neck tumor registry, radiation oncology service, and pathology department were reviewed with attention to presenting symptom, initial examination, diagnostic studies performed, and type and result of biopsies performed.
RESULTS: Thirty-four patients sought treatment for a neck lymph node metastasis of squamous cell carcinoma without an identifiable primary tumor site. Six of these (18%) had the primary site diagnosed by performing tonsillectomy ipsilateral to the presenting neck mass. Six of 14 T1 tonsillar carcinomas in this series had the primary site identified by tonsillectomy.
CONCLUSIONS: Despite a diligent search, a primary tumor site may not be found in the head and neck cancer patient. The tonsil may harbor an occult squamous cell carcinoma. The patient benefits from identification of the initial tumor site because postoperative irradiation ports may be reduced and because surveillance for recurrence may be improved. For these reasons, tonsillectomy should be performed ipsilateral to the presenting cervical metastasis if no other primary tumor site is identified.

Entities:  

Mesh:

Year:  2000        PMID: 10629482     DOI: 10.1016/S0194-5998(00)70143-4

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  16 in total

Review 1.  Management of cervical metastasis.

Authors:  Eric J Lentsch
Journal:  Curr Oncol Rep       Date:  2004-03       Impact factor: 5.075

Review 2.  Carcinoma of unknown primary with hepatic metastases: a need of judicious and contemplative diagnostic algorithm.

Authors:  Vikram Sai Shivaji; Joseph Charles Wilson; Noemi L Schmidt; Orpheus Kolokythas; Neeraj Lalwani
Journal:  Abdom Radiol (NY)       Date:  2020-07-06

Review 3.  Diagnosis and management of neck metastases from an unknown primary.

Authors:  L Calabrese; B A Jereczek-Fossa; J Jassem; A Rocca; R Bruschini; R Orecchia; F Chiesa
Journal:  Acta Otorhinolaryngol Ital       Date:  2005-02       Impact factor: 2.124

4.  Management of neck metastases of unknown primary origin united in two European centers.

Authors:  Jos Straetmans; Julia Vent; Martin Lacko; Ernst-Jan Speel; Christian Huebbers; Robert Semrau; Frank Hoebers; Zlatan Mujagic; Jens-Peter Klussmann; Simon F Preuss; Bernd Kremer
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-03-11       Impact factor: 2.503

5.  Small lymphocytic lymphoma obscuring microscopic tonsillar squamous cell carcinoma: an unknown occurrence with a known primary.

Authors:  Eugen C Minca; Saurin R Popat; Manpreet K Chadha; Mihai Merzianu
Journal:  Head Neck Pathol       Date:  2010-12-01

Review 6.  The prevalence of human papillomavirus in squamous cell carcinoma of unknown primary site metastatic to neck lymph nodes: a systematic review.

Authors:  Paolo Boscolo-Rizzo; Lea Schroeder; Salvatore Romeo; Michael Pawlita
Journal:  Clin Exp Metastasis       Date:  2015-09-10       Impact factor: 5.150

7.  The "small, dark tonsil" in patients presenting with metastatic cervical lymphadenopathy from an unknown primary.

Authors:  Jacque R Jumper; Nancy J Fischbein; Michael J Kaplan; Harvey Z Klein; William P Dillon
Journal:  AJNR Am J Neuroradiol       Date:  2005-02       Impact factor: 3.825

8.  Bilateral synchronous tonsillar carcinoma in cervical cancer of unknown primary site (CUPS).

Authors:  Ilkay Kazak; Andreas Haisch; Sergije Jovanovic
Journal:  Eur Arch Otorhinolaryngol       Date:  2003-05-09       Impact factor: 2.503

9.  Innate immune reactions in locally limited tonsillar cancer.

Authors:  Yuichiro Kuratomi; Kenichiro Kusano; Rintaro Shimazu; Akira Inokuchi
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-03-08       Impact factor: 2.503

10.  Carcinoma of unknown primary origin.

Authors:  Gauri R Varadhachary
Journal:  Gastrointest Cancer Res       Date:  2007-11
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.