J N Myers1, T Elkins, D Roberts, R M Byers. 1. Department of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, Houston, USA.
Abstract
OBJECTIVE: This study was designed to determine whether the incidence of squamous cell carcinoma of the oral tongue (SCCOT) in young adults has changed during the past 25 years and to determine prognostic factors for young adult patients (aged < 40 years) with SCCOT. METHODS AND PATIENTS: A retrospective review of young adults with SCCOT who sought treatment at the M. D. Anderson Cancer Center between 1973 and 1995 was undertaken. RESULTS: The percentage of young adult SCCOT patients at M. D. Anderson increased from 4% in 1971 to 18% in 1993. T stage, N stage, perineural invasion, and lymphatic invasion were all associated with decreased survival. Patients who received a neck dissection as part of their primary treatment had a better chance of survival than patients who did not. CONCLUSIONS: The incidence of SCCOT in the young adult population is increasing in the United States. Appropriate surgical management for young adults with SCCOT includes resection of the primary tumor along with a selective node dissection.
OBJECTIVE: This study was designed to determine whether the incidence of squamous cell carcinoma of the oral tongue (SCCOT) in young adults has changed during the past 25 years and to determine prognostic factors for young adult patients (aged < 40 years) with SCCOT. METHODS AND PATIENTS: A retrospective review of young adults with SCCOT who sought treatment at the M. D. Anderson Cancer Center between 1973 and 1995 was undertaken. RESULTS: The percentage of young adult SCCOT patients at M. D. Anderson increased from 4% in 1971 to 18% in 1993. T stage, N stage, perineural invasion, and lymphatic invasion were all associated with decreased survival. Patients who received a neck dissection as part of their primary treatment had a better chance of survival than patients who did not. CONCLUSIONS: The incidence of SCCOT in the young adult population is increasing in the United States. Appropriate surgical management for young adults with SCCOT includes resection of the primary tumor along with a selective node dissection.
Authors: Alhadi Almangush; Ibrahim O Bello; Ricardo D Coletta; Antti A Mäkitie; Laura K Mäkinen; Joonas H Kauppila; Matti Pukkila; Jaana Hagström; Jussi Laranne; Ylermi Soini; Veli-Matti Kosma; Petri Koivunen; Natalie Kelner; Luiz Paulo Kowalski; Reidar Grénman; Ilmo Leivo; Esa Läärä; Tuula Salo Journal: Virchows Arch Date: 2015-04-03 Impact factor: 4.064
Authors: Ekaterina G Shatalova; Andres J P Klein-Szanto; Karthik Devarajan; Edna Cukierman; Margie L Clapper Journal: Cancer Prev Res (Phila) Date: 2012-12-31
Authors: Richard J Cassidy; Jeffrey M Switchenko; Naresh Jegadeesh; Mutlay Sayan; Matthew J Ferris; Bree R Eaton; Kristin A Higgins; Jeffrey T Wadsworth; Kelly R Magliocca; Nabil F Saba; Jonathan J Beitler Journal: JAMA Otolaryngol Head Neck Surg Date: 2017-04-01 Impact factor: 6.223