Literature DB >> 10628892

Rumination and distraction in major depression: assessing response to pharmacological treatment.

R M Bagby1, N A Rector, Z V Segal, R T Joffe, A J Levitt, S H Kennedy, R D Levitan.   

Abstract

BACKGROUND: Response style theory of depression (RST) predicts that individuals who ruminate in response to their depressed mood will suffer an amplification and prolongation of that mood, whereas individuals who engage in distraction responses will alleviate and attenuate their depressed mood. RST has been shown to predict prolonged depression in samples of non-clinical, untreated individuals with mild to moderate depression but has not been tested in samples of depressed patients undergoing treatment.
OBJECTIVE: In this preliminary investigation we examined: (1) whether RST predicts non-response to pharmacotherapy with outpatients suffering from major depression, and (2) whether distractive and ruminative responses are associated with clinical variables hypothesized to be associated with them.
METHODS: Eighty-nine depressed outpatients being treated with standard antidepressant pharmacotherapy were administered the Response Style Questionnaire, a scale designed to measure rumination and distraction, prior to treatment.
RESULTS: Distraction, but not rumination, predicted change in depression severity over the course of treatment and overall treatment outcome. Neither rumination nor distraction was associated with previous number of depressive episodes or duration of current depressive episode. DISCUSSION: These results provide only partial support for RST as a predictor of treatment response. Future investigations are needed to determine if rumination and distraction are predictive of recurrent depressive episodes in recovered depressed patients. LIMITATIONS: As the data in this study was retrieved from a clinical database, the conclusions of this report must be viewed tentatively. Replication with other clinical samples is needed.

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Year:  1999        PMID: 10628892     DOI: 10.1016/s0165-0327(99)00015-4

Source DB:  PubMed          Journal:  J Affect Disord        ISSN: 0165-0327            Impact factor:   4.839


  5 in total

1.  EFFECTS OF RUMINATION AND INITIAL SEVERITY ON REMISSION TO COGNITIVE THERAPY FOR DEPRESSION.

Authors:  Neil P Jones; Greg J Siegle; Michael E Thase
Journal:  Cognit Ther Res       Date:  2008-08-01

2.  Poor performance on cognitive tasks in depression: Doing too much or not enough?

Authors:  Neil P Jones; Greg J Siegle; Emilie R Muelly; Agnes Haggerty; Frank Ghinassi
Journal:  Cogn Affect Behav Neurosci       Date:  2010-03       Impact factor: 3.282

3.  Brooding and pondering: isolating the active ingredients of depressive rumination with exploratory factor analysis and structural equation modeling.

Authors:  Michael F Armey; David M Fresco; Michael T Moore; Douglas S Mennin; Cynthia L Turk; Richard G Heimberg; Jelena Kecmanovic; Lauren B Alloy
Journal:  Assessment       Date:  2009-08-10

Review 4.  Psychosocial and clinical predictors of response to pharmacotherapy for depression.

Authors:  R Michael Bagby; Andrew G Ryder; Carolina Cristi
Journal:  J Psychiatry Neurosci       Date:  2002-07       Impact factor: 6.186

5.  Restoring mood balance in depression: ketamine reverses deficit in dopamine-dependent synaptic plasticity.

Authors:  Pauline Belujon; Anthony A Grace
Journal:  Biol Psychiatry       Date:  2014-05-06       Impact factor: 13.382

  5 in total

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