Literature DB >> 10627486

Strong FANCA/FANCG but weak FANCA/FANCC interaction in the yeast 2-hybrid system.

T Reuter1, S Herterich, O Bernhard, H Hoehn, H J Gross.   

Abstract

Three of at least 8 Fanconi anemia (FA) genes have been cloned (FANCA, FANCC, FANCG), but their functions remain unknown. Using the yeast 2-hybrid system and full-length cDNA, the authors found a strong interaction between FANCA and FANCG proteins. They also obtained evidence for a weak interaction between FANCA and FANCC. Neither FANCA nor FANCC was found to interact with itself. These results support the notion of a functional association between the FA gene products. (Blood. 2000;95:719-720)

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Year:  2000        PMID： 10627486

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  8 in total

1.  Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair.

Authors:  Justin Wai Chung Leung; Yucai Wang; Ka Wing Fong; Michael Shing Yan Huen; Lei Li; Junjie Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-06       Impact factor: 11.205

2.  Polymorphic variations in the FANCA gene in high-risk non-BRCA1/2 breast cancer individuals from the French Canadian population.

Authors:  Nadhir Litim; Yvan Labrie; Sylvie Desjardins; Geneviève Ouellette; Karine Plourde; Pascal Belleau; Francine Durocher
Journal:  Mol Oncol       Date:  2012-09-11       Impact factor: 6.603

3.  Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms.

Authors:  Fenghua Yuan; Liangyue Qian; Xinliang Zhao; Jesse Y Liu; Limin Song; Gennaro D'Urso; Chaitanya Jain; Yanbin Zhang
Journal:  J Biol Chem       Date:  2011-12-21       Impact factor: 5.157

4.  The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.

Authors:  Chuan Wang; Muriel W Lambert
Journal:  Biochemistry       Date:  2010-07-06       Impact factor: 3.162

5.  Modularized functions of the Fanconi anemia core complex.

Authors:  Yaling Huang; Justin W C Leung; Megan Lowery; Nobuko Matsushita; Yucai Wang; Xi Shen; Do Huong; Minoru Takata; Junjie Chen; Lei Li
Journal:  Cell Rep       Date:  2014-06-05       Impact factor: 9.423

6.  Towards a molecular understanding of the fanconi anemia core complex.

Authors:  Charlotte Hodson; Helen Walden
Journal:  Anemia       Date:  2012-05-22

7.  RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cells.

Authors:  Chun-Hua Dai; Jian Li; Ping Chen; He-Guo Jiang; Ming Wu; Yong-Chang Chen
Journal:  J Biomed Sci       Date:  2015-09-18       Impact factor: 8.410

8.  Defective FANCI binding by a fanconi anemia-related FANCD2 mutant.

Authors:  Koichi Sato; Masamichi Ishiai; Minoru Takata; Hitoshi Kurumizaka
Journal:  PLoS One       Date:  2014-12-09       Impact factor: 3.240
  8 in total

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