Literature DB >> 10626772

Unusual capillary electrophoretic behavior of triplet repeat DNA.

Y Kiba1, Y Baba.   

Abstract

We investigated the electrophoretic behavior of triplet repeat DNA fragments by capillary electrophoresis and found triplet repeat DNA fragments showed unusual mobilities compared with those of commercially available DNA molecular marker. The electrophoretic data are analyzed by means of Ogston model and the mechanism of a change in mobility of triplet repeat DNA is discussed. The unusual mobilities are caused by the characteristic higher-order structure formed by GC-rich triplet repeat DNA.

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Year:  1999        PMID： 10626772     DOI： 10.1016/s0165-022x(99)00044-5

Source DB:  PubMed          Journal:  J Biochem Biophys Methods        ISSN： 0165-022X


  2 in total

Review 1.  Molecular Correlates and Recent Advancements in the Diagnosis and Screening of FMR1-Related Disorders.

Authors:  Indhu-Shree Rajan-Babu; Samuel S Chong
Journal:  Genes (Basel)       Date:  2016-10-14       Impact factor: 4.096

Review 2.  FMR1 CGG repeat expansion mutation detection and linked haplotype analysis for reliable and accurate preimplantation genetic diagnosis of fragile X syndrome.

Authors:  Indhu-Shree Rajan-Babu; Mulias Lian; Felicia S H Cheah; Min Chen; Arnold S C Tan; Ethiraj B Prasath; Seong Feei Loh; Samuel S Chong
Journal:  Expert Rev Mol Med       Date:  2017-07-19       Impact factor: 5.600
  2 in total

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