Literature DB >> 10624891

Inhibition of chemical carcinogenesis by Psoralea corylifolia seeds.

P G Latha1, K R Panikkar.   

Abstract

Psoralea corylifolia L. (Fabaceae) seeds are extensively used in Ayurvedic medicine. Topical application of 100 mg/kg body weight of the active fraction (AF) of P. corylifolia seeds inhibited the growth and delayed the onset of papilloma formation in mice, initiated with 7,12-dimethyl benz(a) anthracene and promoted using croton oil. The AF at the same dose, when administered orally, inhibited the growth of subcutaneously injected 20-methylcholanthrene (MCA)--induced soft tissue fibrosarcomas significantly. The AF has been shown by gas chromatography analysis to be composed of a mixture of glycerides of fatty acids.

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Year:  1999        PMID： 10624891     DOI： 10.1016/s0378-8741(99)00062-8

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  7 in total

1.  In vitro antimicrobial activities of bakuchiol against oral microorganisms.

Authors:  H Katsura; R I Tsukiyama; A Suzuki; M Kobayashi
Journal:  Antimicrob Agents Chemother       Date:  2001-11       Impact factor: 5.191

2.  Psoralidin induces autophagy through ROS generation which inhibits the proliferation of human lung cancer A549 cells.

Authors:  Wenhui Hao; Xuenong Zhang; Wenwen Zhao; Xiuping Chen
Journal:  PeerJ       Date:  2014-09-09       Impact factor: 2.984

3.  Pharmacognostical evaluation of Psoralea corylifolia Linn. seed.

Authors:  Sahara Shrestha; Hasmukh R Jadav; Prashant Bedarkar; B J Patgiri; C R Harisha; Swapnil Y Chaudhari; Pradeep K Prajapati
Journal:  J Ayurveda Integr Med       Date:  2018-08-16

4.  Screening Antitumor Compounds Psoralen and Isopsoralen from Psoralea corylifolia L. Seeds.

Authors:  Yi Wang; Chengtao Hong; Chenguang Zhou; Dongmei Xu; Hai-Bin Qu
Journal:  Evid Based Complement Alternat Med       Date:  2011-03-10       Impact factor: 2.629

5.  Development of an HPLC Method for Absolute Quantification and QAMS of Flavonoids Components in Psoralea corylifolia L.

Authors:  Cuiping Yan; Yu Wu; Zebin Weng; Qianqian Gao; Guangming Yang; Zhipeng Chen; Baochang Cai; Weidong Li
Journal:  J Anal Methods Chem       Date:  2015-10-26       Impact factor: 2.193

6.  Diverse role of fast growing rhizobia in growth promotion and enhancement of psoralen content in Psoralea corylifolia L.

Authors:  Chandra Prabha; D K Maheshwari; Vivek K Bajpai
Journal:  Pharmacogn Mag       Date:  2013-10       Impact factor: 1.085

Review 7.  Phytochemical and Pharmacological Studies on the Genus Psoralea: A Mini Review.

Authors:  Cong-Cong Li; Teng-Long Wang; Zhong-Qun Zhang; Wen-Qiang Yang; Yue-Fei Wang; Xin Chai; Chun-Hua Wang; Zheng Li
Journal:  Evid Based Complement Alternat Med       Date:  2016-11-17       Impact factor: 2.629
  7 in total

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