BACKGROUND: Cytomegalovirus retinitis seems to be an uncommon complication in African AIDS patients. This study was conducted in 200 patients in order to evaluate AIDS eye related complications with specific focus to cytomegalovirus retinitis. MATERIAL AND METHODS: During a period of 20 months, 200 patients (83 men and 117 women) presenting WHO AIDS case definition diagnosis were enrolled for a complete ocular examination comprising external, anterior segment and retinal fundus and fluorescein angiographic examination. RESULTS: For the whole, 200 patients underwent ocular examinations; of them 121 (60.5%) developed ocular complications. The most frequent complications were cotton wool spots (25.5%), cytomegalovirus (CMV) retinitis (21.5%), retinal hemorrhage (6%), papilloedema (3%), chorioretinal toxoplasmosis (3%), peripheral retinal vascularitis (2. 5%), herpes zoster ophthalmicus (2%). Among those with CMV retinitis, bilateral lesions were found in 30 cases, and unilateral ones in 13 cases. Poor vision was associated with the presence of CMV retinitis in 88% of cases. Death occurred in a mean range of 22 days after the "presumed" diagnosis of CMV retinitis. CONCLUSION: Cytomegalovirus retinitis represents the second ocular complication in AIDS patients in this study. Poor visual outcome was associated in 88% of cases. These results demonstrate that in some west African countries, CMV retinitis may be a common complication in AIDS patients.
BACKGROUND:Cytomegalovirus retinitis seems to be an uncommon complication in African AIDSpatients. This study was conducted in 200 patients in order to evaluate AIDS eye related complications with specific focus to cytomegalovirus retinitis. MATERIAL AND METHODS: During a period of 20 months, 200 patients (83 men and 117 women) presenting WHO AIDS case definition diagnosis were enrolled for a complete ocular examination comprising external, anterior segment and retinal fundus and fluorescein angiographic examination. RESULTS: For the whole, 200 patients underwent ocular examinations; of them 121 (60.5%) developed ocular complications. The most frequent complications were cotton wool spots (25.5%), cytomegalovirus (CMV) retinitis (21.5%), retinal hemorrhage (6%), papilloedema (3%), chorioretinal toxoplasmosis (3%), peripheral retinal vascularitis (2. 5%), herpes zoster ophthalmicus (2%). Among those with CMV retinitis, bilateral lesions were found in 30 cases, and unilateral ones in 13 cases. Poor vision was associated with the presence of CMV retinitis in 88% of cases. Death occurred in a mean range of 22 days after the "presumed" diagnosis of CMV retinitis. CONCLUSION:Cytomegalovirus retinitis represents the second ocular complication in AIDSpatients in this study. Poor visual outcome was associated in 88% of cases. These results demonstrate that in some west African countries, CMV retinitis may be a common complication in AIDSpatients.
Authors: Somsanguan Ausayakhun; Alison H Skalet; Choeng Jirawison; Sakarin Ausayakhun; Jeremy D Keenan; Claire Khouri; Khang Nguyen; Partho S Kalyani; David Heiden; Gary N Holland; Todd P Margolis Journal: Am J Ophthalmol Date: 2011-09-08 Impact factor: 5.258
Authors: Paulina Ocieczek; James R Barnacle; Joe Gumulira; Sam Phiri; Tom Heller; Iwona Grabska-Liberek Journal: Open Forum Infect Dis Date: 2019-11-06 Impact factor: 3.835
Authors: David Heiden; Nathan Ford; David Wilson; William R Rodriguez; Todd Margolis; Bart Janssens; Martha Bedelu; Nini Tun; Eric Goemaere; Peter Saranchuk; Kalpana Sabapathy; Frank Smithuis; Emmanuel Luyirika; W Lawrence Drew Journal: PLoS Med Date: 2007-12 Impact factor: 11.069