N K Tonks1, M P Myers. Show Affiliations » 1. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. tonks@cshl.org
Abstract
Entities: Disease
Mesh： See more » AnimalsBinding SitesCell Membrane/metabolismCrystallography, X-RayGenes, Tumor SuppressorHumansHydrogen BondingMembrane Lipids/metabolismModels, BiologicalMutationNeoplasms/etiologyNeoplasms/geneticsPTEN PhosphohydrolasePhosphatidylinositol 3-Kinases/chemistryPhosphatidylinositol 3-Kinases/metabolismPhosphatidylinositol Phosphates/metabolismPhosphoric Monoester Hydrolases/chemistryPhosphoric Monoester Hydrolases/geneticsPhosphoric Monoester Hydrolases/metabolismPhosphorylationProtein ConformationProtein FoldingProtein Structure, SecondaryProtein Structure, TertiarySignal TransductionTumor Suppressor Proteins
Substances： See more » Membrane LipidsPhosphatidylinositol PhosphatesTumor Suppressor Proteinsphosphatidylinositol 3,4,5-triphosphatePhosphatidylinositol 3-KinasesPhosphoric Monoester HydrolasesPTEN PhosphohydrolasePTEN protein, human
Year: 1999 PMID： 10617421 DOI： 10.1126/science.286.5447.2096
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728