Literature DB >> 10617079

Tokaramide A, a new cathepsin B inhibitor from the marine sponge Theonella aff. mirabilis.

N Fusetani1, M Fujita, Y Nakao, S Matsunaga, R W Van Soest.   

Abstract

A new cathepsin B inhibitor, tokaramide A (1) has been isolated from the marine sponge Theonella aff. mirabilis. Its structure was determined by spectroscopic and chemical methods. Tokaramide A inhibits cathepsin B with an IC50 value of 29.0 ng/mL.

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Year:  1999        PMID： 10617079     DOI： 10.1016/s0960-894x(99)00618-6

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

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Authors:  Ahmed M Sayed; Amira R Khattab; Asmaa M AboulMagd; Hossam M Hassan; Mostafa E Rateb; Hala Zaid; Usama Ramadan Abdelmohsen
Journal:  RSC Adv       Date:  2020-05-27       Impact factor: 4.036

2.  Identification of the protease inhibitor miraziridine A in the Red sea sponge Theonella swinhoei.

Authors:  Paula Tabares; Björn Degel; Norbert Schaschke; Ute Hentschel; Tanja Schirmeister
Journal:  Pharmacognosy Res       Date:  2012-01

Review 3.  The Key Role of Lysosomal Protease Cathepsins in Viral Infections.

Authors:  Melania Scarcella; Danila d'Angelo; Mariangela Ciampa; Simona Tafuri; Luigi Avallone; Luigi Michele Pavone; Valeria De Pasquale
Journal:  Int J Mol Sci       Date:  2022-08-13       Impact factor: 6.208

4.  Practical synthesis of peptide C-terminal aldehyde on a solid support.

Authors:  Hiroyuki Konno; Yoshihiro Sema; Manabu Ishii; Yasunao Hattori; Kazuto Nosaka; Kenichi Akaji
Journal:  Tetrahedron Lett       Date:  2013-06-28       Impact factor: 2.415
  4 in total

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