Literature DB >> 10616966

Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook. fruit powder in alloxan-diabetic rats.

B K Rao1, M M Kesavulu, R Giri, C Appa Rao.   

Abstract

This study was undertaken to investigate the effect of Momordica cymbalaria fruit powder on blood glucose and other biochemical parameters in alloxan-induced diabetic rats. The treatment was given for 15 days. After the treatment, a significant reduction was observed in fasting blood glucose levels in the treated diabetic rats, but no hypoglycaemic activity in the treated normal rats. M. cymbalaria treatment showed considerable lowering of serum cholesterol and triglycerides in the treated diabetic group. There was a significant improvement in hepatic glycogen level in treated diabetic rats close to normal level after the treatment with M. cymbalaria. These results suggest that the M. cymbalaria fruit powder possesses antidiabetic and hypolipidemic effects in alloxan-induced diabetic rats.

Entities:  

Mesh：

Substances：

Year:  1999        PMID： 10616966     DOI： 10.1016/s0378-8741(99)00004-5

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  28 in total

1.  Antihyperglycemic and hypolipidemic effects of Helicteres isora roots in alloxan-induced diabetic rats: a possible mechanism of action.

Authors:  Sama Venkatesh; B Madhava Reddy; G Dayanand Reddy; Ramesh Mullangi; M Lakshman
Journal:  J Nat Med       Date:  2010-03-18       Impact factor: 2.343

Review 2.  Phytotherapy in diabetes: Review on potential mechanistic perspectives.

Authors:  Hanan S El-Abhar; Mona F Schaalan
Journal:  World J Diabetes       Date:  2014-04-15

3.  Comparative study of three angiotensin II type 1 receptor antagonists in preventing liver fibrosis in diabetic rats: stereology, histopathology, and electron microscopy.

Authors:  Sare Sipal; Zekai Halici; Ilhami Kiki; Beyzagul Polat; Abdulmecit Albayrak; Fatih Albayrak; Emre Karakus; Selina Aksak; Berna Ozturk; Cemal Gundogdu
Journal:  J Mol Histol       Date:  2012-08-26       Impact factor: 2.611

Review 4.  Targeting AMPK signaling in combating ovarian cancers: opportunities and challenges.

Authors:  Mingo M H Yung; Hextan Y S Ngan; David W Chan
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2016-01-12       Impact factor: 3.848

5.  Evaluation of the hypoglycemic and hypolipidemic effects of an ethylacetate fraction of Artocarpus heterophyllus (jak) leaves in streptozotocin-induced diabetic rats.

Authors:  S Chackrewarthy; M I Thabrew; M K B Weerasuriya; S Jayasekera
Journal:  Pharmacogn Mag       Date:  2010-07       Impact factor: 1.085

6.  Antidiabetic and Free Radicals Scavenging Potential of Euphorbia hirta Flower Extract.

Authors:  S Kumar; R Malhotra; D Kumar
Journal:  Indian J Pharm Sci       Date:  2010-07       Impact factor: 0.975

7.  Assessment of antidiabetic potential of Cinnamomum tamala leaves extract in streptozotocin induced diabetic rats.

Authors:  Shradha Bisht; S S Sisodia
Journal:  Indian J Pharmacol       Date:  2011-09       Impact factor: 1.200

8.  Antiulcer activity of aqueous extract of fruits of Momordica cymbalaria Hook f. in Wistar rats.

Authors:  P Bharathi Dhasan; M Jegadeesan; S Kavimani
Journal:  Pharmacognosy Res       Date:  2010-01

9.  A pharmacological appraisal of medicinal plants with antidiabetic potential.

Authors:  Vasim Khan; Abul Kalam Najmi; Mohd Akhtar; Mohd Aqil; Mohd Mujeeb; K K Pillai
Journal:  J Pharm Bioallied Sci       Date:  2012-01

10.  Anti-hyperglycaemic activity of swietenia macrophylla king (meliaceae) seed extracts in normoglycaemic rats undergoing glucose tolerance tests.

Authors:  Mohd Akmal Hashim; Mun Fei Yam; Sook Yee Hor; Chung Pin Lim; Mohd Zaini Asmawi; Amirin Sadikun
Journal:  Chin Med       Date:  2013-05-17       Impact factor: 5.455
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.